Non-Hodgkins Lymphoma News
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Latest Non-Hodgkins Lymphoma News By Stage
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More AAcute Lymphoblastic Leukemia
Iclusig Approved for CML and ALL (January 4, 2013)
The U.S. Food and Drug Administration (FDA) has approved Iclusig™ (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases. Chronic... Continue Reading
Blinatumomab Prolongs Survival in Relapsed/Refractory Adult ALL (December 14, 2012)Blinatumomab induces high complete remission rates and prolongs survival in adult patients with relapsed/refractory B-precursor acute lymphoblastic lymphoma (ALL), according to the results of a study presented at the 54th Annual Meeting of the American... Continue Reading
Marqibo Approved for Treatment of Philadelphia-Negative ALL (August 17, 2012)The U.S. Food and Drug Administration (FDA) has approved Marqibo® (vincristine sulfate liposome injection) to treat adults with Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL) whose leukemia has returned or progressed following... Continue Reading
One Subset of Childhood Acute Lymphoblastic Leukemia is Best Treated with Chemotherapy (April 20, 2012)A subset of young patients with acute lymphoblastic leukemia (ALL) who fail to achieve remission after the initial weeks of intense chemotherapy known as induction therapy appear to have better outcomes with additional chemotherapy rather than bone marrow... Continue Reading
Survival Continues to Improve Among Children and Adolescents with ALL (March 15, 2012)Between 1990 and 2005, five-year survival for children and adolescents with acute lymphoblastic leukemia (ALL) increased from 83.7 percent to 90.4 percent. These results were published in the Journal of Clinical Oncology. ALL—a fast-growing cancer of... Continue Reading
More Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia
CPX-351 Highly Active in Older Patients with AML (January 18, 2013)
CPX-351 is highly active in all patient subgroups and produced the greatest benefits in response rate and reduction in 60-day mortality compared to standard therapy in older patients with secondary acute myeloid leukemia and adverse cytogenetics, according... Continue Reading
Combination of Revlimid and Vidaza Beneficial in Untreated Elderly Patients with AML (January 14, 2013)The sequential combination of Vidaza® (azacitidine) and Revlimid® (lenalidomide) shows evidence of clinical activity as initial therapy for older patients with acute myeloid leukemia, according to the results of a phase II study presented at the 54th... Continue Reading
Quizartinib Shows Promise in Treatment-Resistant AML (December 19, 2012)The targeted agent quizartinib showed promise in the treatment of a subset of patients with treatment-resistant acute myeloid leukemia (AML), according to the results of a study presented at the 54th Annual Meeting of the American Society of Hematology... Continue Reading
Gene Mutations Linked with AML Outcome (March 28, 2012)Among patients with acute myeloid leukemia (AML), those with certain genetic changes may benefit from high-dose induction chemotherapy. These results were published in the New England Journal of Medicine. Acute myeloid leukemia is a cancer of the bone... Continue Reading
Mini-Transplants Continue to Show Promise for Older Patients with AML (November 10, 2011)Less toxic cancer treatment followed by an allogeneic stem cell transplant is showing promise for older patients with advanced blood and bone marrow cancers such as acute myeloid leukemia (AML). These results were published in the Journal of the American... Continue Reading
More Acute Myeloid LeukemiaAcute Promyelocytic Leukemia
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)
A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Acute Promyelocytic LeukemiaAdjuvant (I-III, A-C) Colon Cancer
Genomic Testing May Reduce Medical Costs for Colon Cancer (June 14, 2013)
Use of the Oncotype DX® colon cancer test to guide treatment decisions may reduce medical costs and improve patient well-being. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). The Oncotype... Continue Reading
Second Large Study Confirms Oncotype DX Can Predict Recurrence in Stage 2 Colon Cancer (April 22, 2013)Results from the large CALGB 9581 clinical validation study of the Oncotype DX® colon cancer test confirm that Recurrence Score® (RS) results improve the ability to differentiate high recurrence risk disease from low recurrence risk disease, beyond... Continue Reading
Oncotype DX in Colon Cancer May Reduce Medical Costs and Improve Patient Wellbeing (February 20, 2013)The results of two studies evaluating Oncotype DX were presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco and the data indicated that the colon cancer test may reduce medical costs, improve patient wellbeing, and change treatment... Continue Reading
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Oncotype DX Predicts Risk of Colon Cancer Recurrence (October 2, 2012)Among patients with Stage II or Stage III colon cancer, the Oncotype DX colon cancer test provides information about risk of cancer recurrence and overall survival, and may help guide treatment decisions. These results were presented at the European Society... Continue Reading
More Adjuvant (I-III, A-C) Colon CancerAdult Acute Lymphoblastic Leukemia
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)
A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Adult Acute Lymphoblastic LeukemiaAdvanced Stage Hodgkin's Lymphoma
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)
Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
Similar Overall Survival with ABVD and BEACOPP for Advanced Hodgkin’s Lymphoma (July 25, 2011)Although the BEACOPP chemotherapy regimen produces better initial tumor control than the commonly used and less toxic ABVD regimen, the two regimens produce similar overall survival among patients with advanced Hodgkin’s lymphoma. These results were... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Hodgkin’s Survivors at Increased Risk of Stroke (June 24, 2009)Hodgkin’s Survivors at Increased Risk of Stroke Patients who have been treated with radiation therapy for Hodgkin’s lymphoma have an elevated risk of stroke. These results were published in the Journal of the National Cancer Institute. Hodgkin’s... Continue Reading
Better Prognosis for Patients with Lymphocyte-predominant Hodgkin’s Lymphoma (March 8, 2009)Better Prognosis for Patients with Lymphocyte-predominant Hodgkin’s Lymphoma A recent study compared lymphocyte-predominant Hodgkin’s lymphoma (LPHL) and classical Hodgkin’s lymphoma (cHL) in order to define differences in patient characteristics... Continue Reading
More Advanced Stage Hodgkin's LymphomaAdvisory Complementary Alternative Medicine
Combination of Herceptin® with Non–anthracycline-based Chemotherapy Appears to Be Effective (December 15, 2009)
Among women with early, HER2-positive breast cancer, the addition of Herceptin® (trastuzumab) to adjuvant chemotherapy reduces the risk of cancer recurrence and improves survival. Herceptin provides a benefit in combination with either anthracycline-... Continue Reading
More Advisory Complementary Alternative MedicineAggressive/Intermediate Grade Non-Hodgkin's Lymphoma
Rituxan May Prevent Need for Radiation in Mediastinal B-Cell Lymphoma (May 31, 2013)
A dose-adjusted, infusion approach to aggressive chemotherapy with Rituxan® (rituximab) may allow patients with primary mediastinal B-cell lymphoma to skip radiation, according to the results of a study published in the New England Journal of Medicine. Non-Hodgkin’s... Continue Reading
RIT Conditioning with Zevalin Prior to Autologous Transplantation Improves Overall Survival in Patients with DLCL (April 5, 2013)Radioimmunotherapy conditioning with Zevalin® (ibritumomab tiuxetan) prior to autologous stem cell transplantation in patients with diffuse large cell lymphoma offers a similar relapse incidence to total body irradiation, but has lower toxicity and improved... Continue Reading
Treanda Plus Rituxan is Not Inferior to R-CHOP and R-CVP for advanced NHL (April 2, 2013)The combination of Treanda® (bendamustine) and Rituxan® (rituximab) was found to be noninferior to the commonly used chemotherapy regimens R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) and R-CVP (rituximab plus cyclophosphamide,... Continue Reading
Zevalin Plus Nonmyeloablative Allogeneic Transplantation Effective in High-Risk B-Cell NHL (March 29, 2013)The addition of Zevalin® (ibritumomab tiuxetan) to nonmyeloablative allogeneic transplantation (NMAT) is safe and produces early responses and prolonged disease control in high-risk patients with B-cell non-Hodgkin’s lymphoma, according to the results... Continue Reading
Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading
More Aggressive/Intermediate Grade Non-Hodgkin's LymphomaAll Cancer Types
Antidepressant Cymbalta May Reduce Pain from Chemotherapy-Induced Peripheral Neuropathy (May 24, 2013)
The antidepressant Cymbalta® (duloxetine) appears to reduce the numbness and tingling associated with taxane or platinum-based chemotherapy, according to the results of a study published in the Journal of the American Medical Association. Peripheral... Continue Reading
Number of Cancer Survivors Expected to Reach 18 Million by 2022 (May 1, 2013)As of January 2012, there were approximately 13.7 million cancer survivors in the United States and that number is expected to rise by 31 percent to 18 million by 2022, according to the second Annual Report on Cancer Survivorship in the United States published... Continue Reading
Heart Healthy Lifestyle Can Reduce Cancer Risk (April 19, 2013)Following a heart-healthy lifestyle to reduce the risk for heart disease can also help prevent cancer, according to the results of a study published in Circulation. The American Heart Association designed their educational program My Life Check® in order... Continue Reading
Familial Cancer Risk Present in Both Young and Older Diagnosis (January 30, 2013)Although early onset cancers tend to have a more pronounced hereditary component than cancers that develop at a later age, there is still an increased risk of some familial cancers even when a parent is diagnosed at an older age, according to the results... Continue Reading
Exercise Reduces Cancer-Related Fatigue (November 30, 2012)Aerobic exercise can relieve the fatigue associated with cancer and its treatment, according to an updated systematic review published in The Cochrane Library. Fatigue is one of the most common side effects of cancer and its treatment. There are many... Continue Reading
More All Cancer TypesAllogeneic Stem Cell Transplant
Antiretroviral Drug May Prevent Graft-Versus-Host Disease (August 6, 2012)
The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according to the results of a study published in the New... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
Statins May Reduce Acute Graft-versus-host Disease (March 8, 2009)Statins May Reduce Acute Graft-versus-host Disease Researchers from Ohio State University have reported that statins may reduce the risk of developing acute graft-versus-host disease (GVHD) among patients who undergo allogeneic stem cell transplants.... Continue Reading
Stem Cell Transplant Procedures Vary Throughout the World (March 8, 2009)Stem Cell Transplant Procedures Vary Throughout the World Stem cell transplant practices vary substantially among physicians treating adults and children with hematologic malignancies (cancers of the blood or bone marrow such as leukemias and lymphomas).... Continue Reading
More Allogeneic Stem Cell TransplantAlphabetical Sort
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More Alphabetical SortAlternative Medical Systems Complementary Alternative Medicine
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More Alternative Medical Systems Complementary Alternative MedicineAnal Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Anal Cancer Rates Appear to Be On the Rise in the U.S. (May 6, 2013)The number of people in the United States with anal cancer has tripled since the 1970s, according to the results of a study published in the Journal of Clinical Oncology. Anal cancer is an uncommon type of cancer that occurs in the anal canal, the opening... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Anal Cancer on the Rise in Men with HIV (October 15, 2012)Nearly one-third of men with anal cancer have the human immunodeficiency virus (HIV), according to the results of a study published in the Journal of the National Cancer Institute. Anal cancer is an uncommon type of cancer that occurs in the anal canal,... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
More Anal CancerAutologous Stem Cell Transplant
Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)
Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Stem Cell Transplant Procedures Vary Throughout the World (March 8, 2009)Stem Cell Transplant Procedures Vary Throughout the World Stem cell transplant practices vary substantially among physicians treating adults and children with hematologic malignancies (cancers of the blood or bone marrow such as leukemias and lymphomas).... Continue Reading
More Autologous Stem Cell TransplantB
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More BBarrett's Esophagus Esophageal Cancer
Surgeon Volume Influences Outcomes in Esophageal Cancer (February 6, 2013)
Patients who undergo surgery for esophageal cancer have a much higher chance of long-term survival if the surgeon has performed the operation many times before, according to the results of a study published in the Journal of Clinical Oncology. The esophagus... Continue Reading
Barrett’s Esophagus May Carry Lower Risk of Esophageal Cancer Than Previously Reported (July 8, 2011)Barrett’s esophagus—a condition characterized by abnormal cells in the lower part of the esophagus—may carry a lower risk of esophageal cancer than previously reported. These results were published in the Journal of the National Cancer Institute. The... Continue Reading
More Barrett's Esophagus Esophageal CancerBiologic-Orthomolecular Therapies Complementary Alternative Medicine
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More Biologic-Orthomolecular Therapies Complementary Alternative MedicineBiological Therapy
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More Biological TherapyBladder Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
More Evidence that Diabetes Drugs Increase Risk of Bladder Cancer (August 22, 2012)A popular class of diabetes drugs called thiazolidinediones (TZDs) increases the risk of bladder cancer, according to the results of a study published early online in the Journal of the National Cancer Institute. Bladder cancer is diagnosed in as many... Continue Reading
Diabetes Drugs May Increase Risk of Bladder Cancer (July 26, 2012)A class of drugs called thiazolidinediones has been linked to an increased risk of bladder cancer among adults with type 2 diabetes, according to a study published early online in the Canadian Medical Association Journal. Bladder cancer is diagnosed... Continue Reading
More Bladder CancerBone Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Xgeva Reduces Giant-cell Tumor of the Bone (October 2, 2012)Xgeva® (denosumab) significantly reduced or eliminated tumor giant cells in patients with giant-cell tumor of the bone and also increased new bone formation, according to the results of a phase II study published in Clinical Cancer Research. Giant cell... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Bone CancerBrain Cancer
Avastin Doesn’t Improve Survival in Newly Diagnosed Glioblastoma (June 7, 2013)
In a Phase III clinical trial among patients with newly diagnosed glioblastoma, the addition of Avastin® (bevacizumab) to standard chemoradiation increased side effects and did not improve overall survival. These results were presented at the 2013 Annual... Continue Reading
Agenus Announces Initiation of Enrollment in NCI-Sponsored Randomized Trial of Prophage G-200 Vaccine With Avastin in Treatment of Brain Tumors (May 22, 2013)Study Seeking to Enroll 222 Patients; Largest Vaccine Trial Ever Funded by NCI in Brain Tumors and the Largest Cancer Vaccine Study Ever Conducted in Combination With Avastin LEXINGTON, Mass., May 22, 2013 (GLOBE NEWSWIRE) — Agenus Inc. (Nasdaq:AGEN)... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Early Resection of Low-Grade Gliomas Improves Survival (November 21, 2012)Patients in Norway with low-grade gliomas who were treated with early surgical resection had better overall survival than those treated with biopsy and watchful waiting, according to the results of a study published in the Journal of the American Medical... Continue Reading
More Brain CancerBreast Cancer
Oncotype DX® Predicts Recurrence in Patients with DCIS (June 18, 2013)
The Oncotype DX® DCIS Score predicts the 10-year risk of local recurrence, defined as recurrence of DCIS or invasive breast cancer in the same breast, and can help guide radiation treatment decision-making for women with DCIS who are treated with breast-conserving... Continue Reading
SERMs Reduce Risk of Breast Cancer (June 12, 2013)Women who take selective estrogen receptor modulators (SERMs) have a 38 percent reduced risk of breast cancer for up to 10 years after diagnosis and treatment, according to the results of a meta-analysis published in The Lancet. A majority of breast cancers... Continue Reading
Gene Mutations Common In African American Women with Triple-Negative or Early Onset Breast Cancer (June 10, 2013)Among African-American women with breast cancer referred for genetic counseling, one in five had an inherited mutation in at least one of the 18 genes that are linked with breast cancer susceptibility. The frequency of gene mutations was even higher in... Continue Reading
Breast Cancer Deadlier in Women with Cosmetic Implants (June 7, 2013)Breast cancer appears to be more deadly among women with cosmetic breast implants, according to the results of a study published in the British Medical Journal—possibly because it is detected at a more advanced stage. Approximately 200,000 women are... Continue Reading
Genomic Testing with Oncotype DX Provides Prognostic Information in Stage IV Breast Cancer (June 4, 2013)Among women with Stage IV, estrogen receptor-positive breast cancer, the Oncotype DX® breast cancer test provided information about cancer prognosis; this may help guide treatment decisions. These results were presented at the 2013 Annual Meeting of... Continue Reading
More Breast CancerC
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More CCancer Dictionary
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More Cancer DictionaryCarcinoma In Situ Breast cancer
Oncotype DX® Predicts Recurrence in Patients with DCIS (June 18, 2013)
The Oncotype DX® DCIS Score predicts the 10-year risk of local recurrence, defined as recurrence of DCIS or invasive breast cancer in the same breast, and can help guide radiation treatment decision-making for women with DCIS who are treated with breast-conserving... Continue Reading
Breast Brachytherapy May Result in More Complications (October 31, 2012)Brachytherapy is tied to more wound and skin complications than the standard radiation technique, according to the results of a study published in the Journal of Clinical Oncology. For women with early-stage breast cancer who are treated with breast-conserving... Continue Reading
Physical Activity Linked to Reduced Mortality in Breast and Colon Cancer (May 22, 2012)Physical activity is associated with reduced mortality in patients with breast and colon cancer, according to a study published in the Journal of the National Cancer Institute.[1] So far, there is insufficient evidence to draw the same conclusion with... Continue Reading
Oncotype DX DCIS Score Predicts Recurrence Risk for Women with DCIS (December 8, 2011)A DCIS Score generated by the Oncotype DX breast cancer test provides information about how likely it is that breast ductal carcinoma in situ (DCIS) will recur. This may help guide decisions about whether women with DCIS need radiation therapy after breast-conserving... Continue Reading
Depression Is Prevalent in Partners of Cancer Patients (October 1, 2010)Men whose partners were diagnosed with breast cancer were 39% more likely to be hospitalized due to an affective disorder (major depression, bipolar disease, and other serious mood-altering conditions) compared with men whose partners were not diagnosed... Continue Reading
More Carcinoma In Situ Breast cancerCervical Cancer
Avastin Improves Outcomes for Women with Advanced Cervical Cancer (June 11, 2013)
In a Phase III clinical trial, adding Avastin® (bevacizumab) to chemotherapy prolonged overall survival among women with recurrent or metastatic cervical cancer. These results were presented at the 2013 Annual Meeting of the American Society of Clinical... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
HPV Test Appropriate After Indeterminate Pap Test (April 29, 2013)Women who have an indeterminate Pap smear should undergo human papillomavirus (HPV) testing rather than another Pap smear, according to the results of Cochrane Review. Cancer screening refers to the use of tests to detect cancer in individuals who do... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Gardasil is Safe, According to Large Study (October 12, 2012)The HPV vaccine Gardasil® (quadrivalent human papillomavirus [types 6, 11, 16, 18] recombinant vaccine) was found to be safe, according to the results of a large safety study published in the Archives of Pediatrics & Adolescent Medicine. The study... Continue Reading
More Cervical CancerChemotherapy
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More ChemotherapyChildhood Acute Lymphoblastic Leukemia
One Subset of Childhood Acute Lymphoblastic Leukemia is Best Treated with Chemotherapy (April 20, 2012)
A subset of young patients with acute lymphoblastic leukemia (ALL) who fail to achieve remission after the initial weeks of intense chemotherapy known as induction therapy appear to have better outcomes with additional chemotherapy rather than bone marrow... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Childhood Acute Lymphoblastic LeukemiaChronic Lymphoblastic Leukemia
Ibrutinib Active In Untreated, Relapsed and Unresponsive CLL (June 3, 2013)
The drug ibrutinib was well tolerated and highly effective in patients with untreated, relapsed and unresponsive chronic lymphocytic leukemia—leading to large reductions in tumor burden, according to the results of a study presented at the American... Continue Reading
Lymphoma Patients and Transplant Recipients at Higher Risk of Melanoma (October 11, 2012)Individuals with lymphoma or those who have undergone organ transplants are far more likely than the average person to develop—and die from—melanoma, according to the results of a review published in Mayo Clinic Proceedings. Melanoma is a potentially... Continue Reading
Combination of Campath and Fludarabine Provides Benefit in CLL (February 16, 2012)Among people with previously treated, relapsed or refractory chronic lymphocytic leukemia (CLL), treatment with a combination of Campath® (alemtuzumab) and fludarabine results in better outcomes than treatment with fludarabine alone. These results were... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
More Chronic Lymphoblastic LeukemiaChronic Lymphocytic Leukemia
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)
A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Fludara plus Rituxan Extends Survival in CLL (April 6, 2010)Patients with untreated chronic lymphocytic leukemia experienced prolonged survival when treated with Fludara® (fludarabine) plus Rituxan® (rituximab) (delivered either concurrently or sequentially), according to the results of a study presented... Continue Reading
Rituxan Approved for Chronic Lymphocytic Leukemia (February 24, 2010)The U.S. Food and Drug Administration (FDA) has expanded the approval of Rituxan® (rituximab) to include the treatment of certain patients with chronic lymphocytic leukemia. Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with... Continue Reading
Arzerra™ Approved for Refractory Chronic Lymphocytic Leukemia (October 28, 2009)The targeted therapy Arzerra™ (ofatumumab) has been granted accelerated approval by the U.S. Food and Drug Administration for treatment of patients with chronic lymphocytic leukemia (CLL) that is refractory to Fludara® (fludarabine) and Campath® (alemtuzumab). Chronic... Continue Reading
Abnormal Cells Identified in Blood Years Before Diagnosis of CLL (March 9, 2009)According to the results of a study published in the New England Journal of Medicine, chronic lymphocytic leukemia (CLL) appears to be preceded by a condition known as monoclonal B-cell lymphocytosis (MBL). Chronic lymphocytic leukemia is the most common... Continue Reading
More Chronic Lymphocytic LeukemiaChronic Myeloid Leukemia
Iclusig Approved for CML and ALL (January 4, 2013)
The U.S. Food and Drug Administration (FDA) has approved Iclusig™ (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases. Chronic... Continue Reading
Tasigna Superior to Gleevec for Philadelphia Chromosome-Positive CML (December 21, 2012)Tasigna® (nilotinib) is superior to Gleevec® (imatinib) for the treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia (CML), according to the results of two studies presented at the 54th Annual Meeting of the American... Continue Reading
Synribo Approved for CML (November 8, 2012)The U.S. Food and Drug Administration today approved Synribo (omacetaxine mepesuccinate) to treat adults with chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects older adults. Each year in the United States, approximately... Continue Reading
Bosulif Approved for CML (September 26, 2012)The U.S. Food and Drug Administration (FDA) has approved Bosulif® (bosutinib) to treat chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects older adults. The drug is intended for patients with chronic, accelerated... Continue Reading
Ponatinib Produces High Response Rates in CML (August 13, 2012)Ponatinib, an investigational targeted agent, appears to be significantly effective in treatment-refractory chronic myeloid leukemia (CML) and produces early and lasting responses, according to the preliminary results of a study presented at the 2012... Continue Reading
More Chronic Myeloid LeukemiaClinical Trials Database
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More Clinical Trials DatabaseColon Cancer
Genomic Testing May Reduce Medical Costs for Colon Cancer (June 14, 2013)
Use of the Oncotype DX® colon cancer test to guide treatment decisions may reduce medical costs and improve patient well-being. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). The Oncotype... Continue Reading
Erbitux Plus Chemo Boosts Survival in Patients with Colorectal Cancer and Liver Metastases (May 29, 2013)Adding Erbitux® (cetuximab) to standard chemotherapy might allow some patients with colorectal cancer and inoperable liver metastases to undergo successful surgical resection of the liver metastasis, according to the results of a study published in the Journal... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Second Large Study Confirms Oncotype DX Can Predict Recurrence in Stage 2 Colon Cancer (April 22, 2013)Results from the large CALGB 9581 clinical validation study of the Oncotype DX® colon cancer test confirm that Recurrence Score® (RS) results improve the ability to differentiate high recurrence risk disease from low recurrence risk disease, beyond... Continue Reading
Combo Treatment Effective in Elderly Patients with Metastatic Colorectal Cancer (March 6, 2013)Combination therapy with Avastin® (bevacizumab) and Xeloda® (capecitabine) may be an optimal first-line treatment for treatment-naïve older patients with metastatic colorectal cancer, according to the results of a study presented at the 2013 Gastrointestinal... Continue Reading
More Colon CancerComplementary Alternative Medicine
High Prevalence of CAM Use Among Thyroid Cancer Patients (November 1, 2010)
Among patients with thyroid cancer, use of complementary and alternative medicine is common, with more than 80% reporting use. These results were presented at the 14th International Thyroid Congress. Complementary and alternative medicines are therapies... Continue Reading
Fish Oil Linked to Reduction in Breast Cancer Risk (July 9, 2010)A recent study suggests that regular use of fish oil supplements may reduce the risk of breast cancer. These findings were published in the journal of Cancer Epidemiology, Biomarkers & Prevention.[1] Dietary supplements are a booming business—Americans... Continue Reading
Use of Complementary and Alternative Medicine Common in Pediatric Cancer Patients (April 8, 2010)Pediatric cancer patients commonly use complementary and alternative medicine (CAM), according to a review article recently published in the journal Pediatrics.[1] The landscape of medicine has been dramatically changing over the past several decades.... Continue Reading
Women&Cancer Magazine Features Paula Zahn on Spring 2008 Cover (March 8, 2009)Women&Cancer Magazine Features Paula Zahn on Spring 2008 Cover March 17, 2008 Press Contact: Diana Price dprice@omnihealthmedia.com (208) 727-2108, ext. 202 March 17, 2008-Zahn Appears on Women&Cancer cover, Spring 2008 News anchor... Continue Reading
More Complementary Alternative MedicineCorticosteroid
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More DDrug Dictionary
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More EEarly Stage Hodgkin's Lymphoma
Children with Favorable-Risk Hodgkin’s Lymphoma May Benefit from Limited Radiation Therapy (July 6, 2012)
Children with favorable-risk Hodgkin’s lymphoma who achieve a complete early response to chemotherapy may not require radiation therapy or may undergo limited radiation therapy, according to the results of a study published in the Journal of the American... Continue Reading
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
Limited Therapy May Cure a Significant Fraction of Pediatric Patients with Early-Stage Hodgkin Lymphoma (June 13, 2011)At the 2011 meeting of the American Society of Clinical Oncology, researchers involved in the Pediatric Oncology Study Group (POG) reported that selected pediatric patients with stage I and II Hodgkin lymphoma could be cured without alkylating agent chemotherapy... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Reduced-intensity Treatment May be Effective for Early Hodgkin’s Lymphoma (August 27, 2010)Among patients with early-stage Hodgkin’s lymphoma and a favorable prognosis, it may be possible to reduce the number of chemotherapy cycles and the dose of radiation therapy without adversely affecting outcome. The results of this study were published... Continue Reading
More Early Stage Hodgkin's LymphomaEarly Stage I-II (A-B) Prostate Cancer
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
Study Compares Genomic Testing of Normal and Cancerous Prostate Tissue (June 12, 2013)The Oncotype DX® prostate cancer test—which predicts the aggressiveness of early-stage prostate cancer and may help guide treatment decisions—is more predictive of outcome when used on tumor tissue than when used on adjacent, normal prostate tissue.... Continue Reading
Genomic Test May Help Guide Prostate Cancer Treatment (May 13, 2013)A new genetic test—the Oncotype DX® Prostate Cancer Test—measures the aggressiveness of prostate cancer and may help scores of men choose between immediate treatment or active surveillance. The test was shown to strongly predict aggressiveness of... Continue Reading
Surgery and Radiation for Prostate Cancer Produce Similar Functional Outcomes (February 27, 2013)Men with localized prostate cancer experience declines in sexual, urinary, and bowel function over time, regardless of whether they choose surgery or radiation therapy, according to the results of a study published in the New England Journal of Medicine. Each... Continue Reading
No Difference in Toxicity Between Proton Therapy and IMRT for Prostate Cancer (January 28, 2013)Proton therapy does not reduce toxicity compared with intensity-modulated radiation therapy (IMRT) in men with prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute. Prostate cancer is the most... Continue Reading
More Early Stage I-II (A-B) Prostate CancerEsophageal Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Second-Line Docetaxel Improves Survival in Esophageal and Gastric Cancer (April 3, 2013)Second-line treatment with docetaxel improves overall survival of patients with advanced esophageal and gastric cancer, according to the results of a study presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco. The esophagus is a muscular... Continue Reading
Surgery Improves Survival in Esophageal Cancer (February 21, 2013)Surgery after chemoradiotherapy—which is the standard of care in advanced esophageal cancer—increased overall and disease-free survival compared with chemoradiotherapy alone, according to the results of a study presented at the 2013 Gastrointestinal... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Surgeon Volume Influences Outcomes in Esophageal Cancer (February 6, 2013)Patients who undergo surgery for esophageal cancer have a much higher chance of long-term survival if the surgeon has performed the operation many times before, according to the results of a study published in the Journal of Clinical Oncology. The esophagus... Continue Reading
More Esophageal CancerEwing's Sarcoma Overview
Shorter Chemotherapy Intervals Effective in Ewing Sarcoma (November 1, 2012)
In patients with localized Ewing sarcoma, chemotherapy administered every two weeks is more effective than chemotherapy administered every three weeks, with no increase in toxicity, according to the results of a study published in the Journal of Clinical... Continue Reading
Children with Ewing’s Sarcoma or Astrocytoma Most Likely to Experience Late Recurrence (February 19, 2010)Late recurrence of childhood cancers appears to occur most often in Ewing’s sarcoma and astrocytoma, according to the results of a study published in the Journal of the National Cancer Institute. As cancer treatment has improved and evolved, the number... Continue Reading
Children with Ewing’s Sarcoma or Astrocytoma Most Likely to Experience Late Recurrence (February 19, 2010)Late recurrence of childhood cancers appears to occur most often in Ewing’s sarcoma and astrocytoma, according to the results of a study published in the Journal of the National Cancer Institute. As cancer treatment has improved and evolved, the number... Continue Reading
More Ewing's Sarcoma OverviewExtensive Lung Cancer - Small Cell
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)
Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Prophylactic Cranial Irradiation May Improve Survival in Small Cell Lung Cancer (June 14, 2011)Radiation to the brain prior to detectable spread of cancer to the brain improved survival in patients with both early- and late-stage small cell lung cancer. These results were recently presented at the 2011 meeting of the American Society of Clinical... Continue Reading
Some Patients with Advanced Cancer Continue Screening (October 22, 2010)A significant proportion of patients with advanced cancers continue to undergo cancer screening, even though screening is unlikely to benefit these patients. These findings were recently reported in the Journal of the American Medical Association. Cancer... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
More Extensive Lung Cancer - Small CellF
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More FFollicular Lymphoma
Fractionated Zevalin Effective First-Line Treatment for Advanced Follicular Lymphoma (February 8, 2013)
Fractionated radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is an effective first-line treatment for advanced stage follicular lymphoma and delivers high response rates in patients with high tumor burden, according to the results of... Continue Reading
Zevalin Effective as First-Line Treatment for Advanced Follicular Lymphoma (February 1, 2013)Radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is safe and well tolerated and induces a high rate of clinical and molecular responses when given as first-line treatment to patients with advanced stage follicular lymphoma, according... Continue Reading
Zevalin Effective in Follicular NHL Refractory to Rituximab (January 24, 2013)Radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is effective in patients with non-Hodgkin’s lymphoma that is refractory to treatment with Rituxan® (rituximab), according to the results of a study published in the Journal of Clinical... Continue Reading
Consolidation with Zevalin Significantly Improves Progression-Free Survival in Advanced Follicular Lymphoma (January 10, 2013)Consolidation therapy with Zevalin® (ibritumomab tiuxetan) significantly prolongs progression-free survival and leads to high conversion rates from partial response to complete response in patients with advanced follicular lymphoma, according to the... Continue Reading
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
More Follicular LymphomaG
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More GGastric Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Second-Line Docetaxel Improves Survival in Esophageal and Gastric Cancer (April 3, 2013)Second-line treatment with docetaxel improves overall survival of patients with advanced esophageal and gastric cancer, according to the results of a study presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco. The esophagus is a muscular... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Adjuvant Radiochemotherapy Demonstrates Benefit in Gastric Cancer (September 25, 2012)Adjuvant radiochemotherapy provides strong and persistent benefit in patients who have undergone curative gastric resection, according to the long-term results of a study published in the Journal of Clinical Oncology.[1] Gastric cancer refers to cancer... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
More Gastric CancerGene Therapy
New Substances Added to List of Cancer-Causing Agents (June 21, 2011)
In the most recent version of the National Toxicology Program’s Report on Carcinogens, two new substances have been classified as “known human carcinogens” and six others have been classified as “reasonably anticipated to be human carcinogens.” The... Continue Reading
More Gene TherapyGeneral
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Number of Cancer Survivors Expected to Reach 18 Million by 2022 (May 1, 2013)As of January 2012, there were approximately 13.7 million cancer survivors in the United States and that number is expected to rise by 31 percent to 18 million by 2022, according to the second Annual Report on Cancer Survivorship in the United States published... Continue Reading
Heart Healthy Lifestyle Can Reduce Cancer Risk (April 19, 2013)Following a heart-healthy lifestyle to reduce the risk for heart disease can also help prevent cancer, according to the results of a study published in Circulation. The American Heart Association designed their educational program My Life Check® in order... Continue Reading
Mutation in Immortality Gene Linked to Brain and Other Tumors (April 17, 2013)Newly identified mutations in a gene that makes cells immortal—the TERT promoter gene—appear to play a role in several types of cancer, including three of the most common types of brain tumors, according to the results of a study published in the... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
More GeneralGeneral Bone Cancer
Xgeva Reduces Giant-cell Tumor of the Bone (October 2, 2012)
Xgeva® (denosumab) significantly reduced or eliminated tumor giant cells in patients with giant-cell tumor of the bone and also increased new bone formation, according to the results of a phase II study published in Clinical Cancer Research. Giant cell... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Xgeva Delays Onset of Bone Metastases (September 27, 2011)Among men with prostate cancer that has stopped responding to hormonal therapy, the bone drug Xgeva™ (denosumab) delayed the spread of cancer to the bones. These results were presented at the 2011 European Multidisciplinary Cancer Conference. Androgen... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Denosumab Active Against Giant Cell Tumor of Bone (February 11, 2010)In a Phase II clinical trial, denosumab produced high rates of tumor response among patients with recurrent or unresectable giant cell tumors of bone. These results were published in Lancet Oncology. Denosumab is an investigational drug that targets... Continue Reading
More General Bone CancerGeneral Brain Cancer
Avastin Doesn’t Improve Survival in Newly Diagnosed Glioblastoma (June 7, 2013)
In a Phase III clinical trial among patients with newly diagnosed glioblastoma, the addition of Avastin® (bevacizumab) to standard chemoradiation increased side effects and did not improve overall survival. These results were presented at the 2013 Annual... Continue Reading
Agenus Announces Initiation of Enrollment in NCI-Sponsored Randomized Trial of Prophage G-200 Vaccine With Avastin in Treatment of Brain Tumors (May 22, 2013)Study Seeking to Enroll 222 Patients; Largest Vaccine Trial Ever Funded by NCI in Brain Tumors and the Largest Cancer Vaccine Study Ever Conducted in Combination With Avastin LEXINGTON, Mass., May 22, 2013 (GLOBE NEWSWIRE) — Agenus Inc. (Nasdaq:AGEN)... Continue Reading
Early Resection of Low-Grade Gliomas Improves Survival (November 21, 2012)Patients in Norway with low-grade gliomas who were treated with early surgical resection had better overall survival than those treated with biopsy and watchful waiting, according to the results of a study published in the Journal of the American Medical... Continue Reading
Repeated Surgeries Improve Survival in Glioblastoma (November 13, 2012)Patients with recurrent glioblastoma who undergo multiple surgeries to remove tumors may survive longer than those who undergo only one surgery, according to the results of a study published in the Journal of Neurosurgery. Glioblastoma mutiforme (GBM)... Continue Reading
Chemotherapy Plus Radiation Improves Survival for Anaplastic Oligodendroglioma (October 29, 2012)Some patients with anaplastic oligodendroglioma live substantially longer if they are treated with a combination of chemotherapy and radiation instead of radiation alone, according to the long-term results of two studies published in the Journal of Clinical... Continue Reading
More General Brain CancerGeneral Complementary Alternative Medicine
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More General Complementary Alternative MedicineGeneral Gene Therapy
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More General Gene TherapyGeneral Head and Neck Cancer
Doxepin Reduces Mouth Pain from Radiation for Head and Neck Cancer (November 14, 2012)
The tricyclic antidepressant doxepin reduces oral mucositis in patients who receive radiation for head and neck cancer, according to the results of a study presented at the 54th annual meeting of the American Society for Radiation Oncology in Boston,... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Combined Treatment Provides Benefit for Nasopharyngeal Cancer (February 22, 2012)Among patients with Stage II nasopharyngeal cancer (a type of head and neck cancer), adding chemotherapy to radiation therapy resulted in better survival than radiation therapy alone. These results were published in the Journal of the National Cancer... Continue Reading
Erbitux Approved for New Use in Head and Neck Cancer (November 18, 2011)The US Food and Drug Administration has expanded the approval of Erbitux® (cetuximab) to include the initial treatment, in combination with platinum-based chemotherapy, of selected patients with recurrent or metastatic squamous cell head and neck cancer. Head... Continue Reading
HPV Vaccine Recommended for Boys (November 1, 2011)The Advisory Committee on Immunization Practices of the U.S. Centers for Disease Control and Prevention (CDC) has recommended that boys be vaccinated against human papillomavirus (HPV). Human papillomaviruses (HPV) consist of more than 100 different viruses.... Continue Reading
More General Head and Neck CancerGeneral HIV Related Cancers
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Cancer Burden Has Changed for People with HIV/AIDS (April 14, 2011)Among people living with AIDS in the United States, the frequency of AIDS-defining cancers such as Kaposi sarcoma decreased markedly between 1991 and 2005; the frequency of other types of cancer, however, increased three-fold. These results were published... Continue Reading
Study Evaluates Impact of Highly Active Antiretroviral Therapy (HAART) on Cancer Risk in HIV-infected Men (August 10, 2010)Researchers reported that men infected with human immunodeficiency virus (HIV) are still at an increased risk of lymphoma, Kaposi’s sarcoma (KS), and anal cancer despite the introduction of highly active antiretroviral therapy (HAART). These findings... Continue Reading
More General HIV Related CancersGeneral Lung Cancer
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)
Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Diesel Exhaust Linked to Lung Cancer (June 26, 2012)Diesel exhaust is associated with an increased risk of lung cancer, according to a press release issued by the World Health Organization (WHO).[1] The announcement came after a group of international experts gathered for a weeklong meeting to review the... Continue Reading
New Lung Cancer Screening Guidelines (May 25, 2012)New lung cancer screening guidelines recommend annual CT scans only for a select group of people—those aged 55 to 74 who are current or former smokers. The guidelines are the result of a systematic review by an expert panel from several medical groups... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More General Lung CancerGeneral Malignant Mesothelioma
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
MVP Does Not Provide Benefit in Mesothelioma Patients (May 21, 2008)MVP Does Not Provide Benefit in Mesothelioma Patients The chemotherapy agent Navelbine® (vinorelbine) may improve outcomes for patients with malignant pleural mesothelioma. However, the combination chemotherapy regimen referred to as MVP (mitoxantrone,... Continue Reading
Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer (February 8, 2008)Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer Use of a minimally invasive technique called endoscopy to detect lung cancer may be more effective than more complicated and invasive standard procedures. These findings were... Continue Reading
More General Malignant MesotheliomaGeneral Myelodysplastic Syndrome
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Regular Use of Acetaminophen May Increase Risk of Blood Cancers (May 13, 2011)Long-term, regular use of acetaminophen (Tylenol®) may increase the risk of leukemia and lymphoma. These results were published in the Journal of Clinical Oncology. Some studies have suggested that use of aspirin and other nonsteroidal anti-inflammatory... Continue Reading
Vidaza® Improves Survival in Higher-risk Myelodysplastic Syndromes (March 6, 2009)According to the results of a Phase III clinical trial, treatment with Vidaza® (azacitidine) results in better survival than conventional care among patients with higher-risk myelodysplastic syndromes (MDS). These results were published in Lancet Oncology. Myelodysplastic... Continue Reading
The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies (January 30, 2009)The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies The 2008 annual meeting of the American Society of Clinical Oncology (ASCO), held in Chicago, Illinois, again revealed advances in the treatment of... Continue Reading
More General Myelodysplastic SyndromeGeneral Neuroblastoma
Targeted Agent Xalkori May Benefit Children with Anaplastic Lymphoma (May 23, 2012)
The targeted agent Xalkori® (crizotinib) appears to drastically reduce the size of tumors in children with refractory anaplastic large cell lymphoma, according to the results of a phase I study that will be presented at the annual meeting of the American... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Improved Survival with Busulphan-Melphalan Chemotherapy in Pediatric Neuroblastoma (June 8, 2011)Treatment with high doses of the chemotherapy combination including busulphan and melphalan significantly improves survival and reduces cancer progression among pediatric patients with high-risk neuroblastoma. These results were presented at a plenary... Continue Reading
Reduced Chemotherapy Regimen May Be Effective in Neuroblastoma (November 10, 2010)According to results of a Phase III clinical trial, patients with intermediate-risk neuroblastoma may be effectively treated with reduced doses of chemotherapy given over a shorter period. These findings were published in the New England Journal of Medicine. Neuroblastoma... Continue Reading
More General NeuroblastomaGeneral Renal Cancer
New Treatment Options for Advanced Renal Cell Carcinoma (October 8, 2012)
The results from three phase III trials shed new light on treatment options for patients with advanced renal cell carcinoma. The studies were presented at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna. More than 58,000... Continue Reading
PD-1 Targeted Immune Therapy Shows Promising Activity (June 11, 2012)The investigational drug BMS-936558 caused tumor shrinkage in nearly 25 percent of patients with advanced melanoma, kidney cancer and non-small cell lung cancer (NSCLC), according to the results of a phase I study presented at the 2012 annual meeting... Continue Reading
Partial Nephrectomy is Associated with Improved Survival in Early Stage Kidney Cancer (April 27, 2012)Patients with early stage kidney cancer who had only the tumor removed experienced better survival rates than those who had the entire kidney removed, according to the results of a study published in the Journal of the American Medical Association.[1] Nearly... Continue Reading
Tivozanib Promising for Metastatic Renal Cell Carcinoma (April 23, 2012)Tivozanib (AV-951) was well tolerated and improved median progression-free survival (PFS) in some patients with advanced renal cell carcinoma (RCC), according to the results of a phase II study published in the Journal of Clinical Oncology. More than... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More General Renal CancerGeneral Retinoblastoma
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Retinoblastoma Survivors Face Risk of Second Cancers (March 8, 2009)Retinoblastoma Survivors Face Risk of Second Cancers A study that followed retinoblastoma survivors for up to 61 years reported a high risk of second cancers among survivors of hereditary retinoblastoma. These results were published in the Journal of... Continue Reading
Chemotherapy for Retinoblastoma Delivered Directly into Eye May Save Eye (March 8, 2009)Chemotherapy for Retinoblastoma Delivered Directly into Eye May Save Eye Chemotherapy delivered directly into the artery of the eye may save the eyeball in children with retinoblastoma. These results were recently published in an early online publication... Continue Reading
More General RetinoblastomaGeneral Sarcoma
FDA Updates Use of Gleevec for Gastrointestinal Stromal Tumors (February 29, 2012)
In changes approved by the US Food and Drug Administration (FDA), the prescribing information for Gleevec® (imatinib) now notes that three years of adjuvant (post-surgery) treatment results in better survival than one year of adjuvant treatment among... Continue Reading
Halaven Promising in Soft-Tissue Sarcoma (September 26, 2011)The chemotherapy drug Halaven™ (eribulin mesylate) may be a promising therapy for certain types of soft-tissue sarcoma. These findings were recently reported in the Lancet Oncology. Halaven—which was derived from a marine sponge—is a chemotherapy... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Three Years of Treatment with Gleevec Improves Survival in Gastrointestinal Stromal Tumors (GIST) (June 9, 2011)Treatment with Gleevec® (imatinib) for 3 years following surgery significantly improves survival compared with the standard one-year therapy for patients with gastrointestinal stromal tumors (GIST). GIST is a type of soft tissue sarcoma that develops... Continue Reading
Nexavar Shows Promise against Drug-Resistant GIST (February 1, 2011)Among patients with gastrointestinal stromal tumors (GIST) that were resistant to both Gleevec® (imatinib) and Sutent® (sunitinib), treatment with Nexavar® (sorafenib) resulted in tumor shrinkage or stable disease in 68% of patients. The results of... Continue Reading
More General SarcomaGeneral Skin Cancer
Some Squamous Cell Skin Cancers Are Deadly (June 19, 2013)
Cutaneous squamous cell carcinoma is usually easily treated with surgery; however, a subsection of patients with specific disease risk factors are more likely to develop metastases and die from the disease, according to the results of a study published... Continue Reading
Coffee Might Reduce the Risk of Basal Cell Carcinoma (July 11, 2012)Good news for coffee lovers—drinking caffeinated coffee could lower the risk of developing basal cell carcinoma, according to the results of a study published in Cancer Research. The Harvard study found that increased caffeine intake was associated... Continue Reading
Erivedge Effective in Basal-Cell Carcinoma (June 21, 2012)The targeted agent Erivedge™ (vismodegib) is associated with tumor responses in patients with locally advanced or metastatic basal-cell carcinoma and may even reduce the rate of new basal-cell carcinomas, according to the results of two studies published... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Increased Skin Cancer Risk Among Those with Inflammatory Bowel Disease (November 29, 2011)People with inflammatory bowel disease (IBD) may be at increased risk of non-melanoma skin cancer, particularly if they receive immune-suppressing medications such as thiopurines. These were the results of two studies published in Gastroenterology. Crohn’s... Continue Reading
More General Skin CancerGeneral Thyroid Cancer
BRAF V600E mutation Increases Death Risk in Papillary Thyroid Cancer (June 5, 2013)
The presence of the BRAF V600E mutation is significantly associated with increased cancer-related death among patients with papillary thyroid cancer, according to the results of a study published in the Journal of the American Medical Association. The... Continue Reading
Selumetinib May Reverse Radioiodine Resistance in Advance Thyroid Cancer (March 28, 2013)The experimental drug selumetinib (AZD6244) may help some patients with advanced thyroid cancer overcome resistance to radioiodine, which is the most effective treatment for the disease, according to the results of a study published in the New England... Continue Reading
Targeted Drug Caprelsa Slows Thyroid Cancer (August 30, 2012)The targeted drug Caprelsa® (vandetanib) delays progression in advanced differentiated thyroid cancer, according to the results of a study published in The Lancet Oncology. The thyroid is a gland in the throat that produces hormones mostly related to... Continue Reading
Gene Expression Test Identifies Low-Risk Thyroid Nodules (June 28, 2012)A new test measures gene expression in thyroid nodules with inconclusive biopsy results and helps identify low-risk nodules, thereby preventing unnecessary surgeries, according to the results of a study published early online in the New England Journal... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More General Thyroid CancerGeneral Vaginal Cancer
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
DES Daughters Have Increased Risk of Cancer (October 18, 2011)According to a study published in the New England Journal of Medicine, women exposed to diethylstilbestrol (DES) before birth have an increased risk of vaginal cancer, cervical precancers, and breast cancer. These women also have an increased risk for... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Tumor Burden in Sentinel Node May Help Stratify High- and Low-risk Vulvar Cancer Patients (June 15, 2010)Tumor burden in the sentinel node of early-stage vulvar cancer patients appears to be an important prognostic factor. Patients with sentinel-node metastasis larger than 2mm may have a worse prognosis. These findings were recently published in the journal... Continue Reading
More General Vaginal CancerH
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More HHairy Cell Leukemia
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)
A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Hairy Cell LeukemiaHead and Neck Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Doxepin Reduces Mouth Pain from Radiation for Head and Neck Cancer (November 14, 2012)The tricyclic antidepressant doxepin reduces oral mucositis in patients who receive radiation for head and neck cancer, according to the results of a study presented at the 54th annual meeting of the American Society for Radiation Oncology in Boston,... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Head and Neck CancerHealth and Wellness
Heart Healthy Lifestyle Can Reduce Cancer Risk (April 19, 2013)
Following a heart-healthy lifestyle to reduce the risk for heart disease can also help prevent cancer, according to the results of a study published in Circulation. The American Heart Association designed their educational program My Life Check® in order... Continue Reading
Smoking Linked to Increased Risk of Breast Cancer (March 14, 2013)Women who smoke—and especially those who started smoking prior to the birth of their first child—have an increased risk of breast cancer, according to the results of a study published in the Journal of the National Cancer Institute. The study indicates... Continue Reading
Familial Cancer Risk Present in Both Young and Older Diagnosis (January 30, 2013)Although early onset cancers tend to have a more pronounced hereditary component than cancers that develop at a later age, there is still an increased risk of some familial cancers even when a parent is diagnosed at an older age, according to the results... Continue Reading
Hormone Replacement Therapy in Newly Menopausal Women May Carry More Benefit Than Risk (October 26, 2012)Hormone replacement therapy for newly menopausal women may not be as risky as once believed, according to the results of a study presented at the 23rd annual meeting of the North American Menopause Society in Orlando, Florida in October 2012.[1] In fact,... Continue Reading
Multivitamins May Cut Cancer Risk (October 25, 2012)Daily supplementation with multivitamins modestly but significantly reduced the risk of cancer in healthy male doctors who took them for more than 10 years, according to the results of a study published in the Journal of the American Medical Association. The... Continue Reading
More Health and WellnessHepatocellular Carcinoma Liver Cancer
Antiviral Therapy May Reduce the Risk of Tumor Recurrence in HBV-Related Liver Cancer (November 26, 2012)
Patients with hepatitis B-related liver cancer who receive antiviral drugs after curative surgery have a lower risk of recurrence compared to those who do not receive antiviral therapy, according to the results of a study published in the Journal of the... Continue Reading
Sutent® Not Effective for Advanced Liver Cancer (July 10, 2009)In a Phase II clinical trial, patients with inoperable, advanced hepatocellular (liver) cancer did not benefit from treatment with the targeted therapy Sutent® (sunitinib). The results of this study were published in Lancet Oncology. Hepatocellular carcinoma... Continue Reading
Women with Hypothyroidism at Increased Risk of Liver Cancer (June 22, 2009)Women with Hypothyroidism at Increased Risk of Liver Cancer Long-term hypothyroidism in women significantly increases the risk of developing hepatocellular carcinoma (liver cancer), according to the results of a study published in Hepatology.[1] The liver... Continue Reading
Increased Risk of Liver Cancer for Patients with Cirrhosis Who Overexpress EGF (March 8, 2009)Increased Risk of Liver Cancer for Patients with Cirrhosis Who Overexpress EGF According to an article recently published in the Journal of the American Medical Association, patients with cirrhosis of the liver who overexpress epithelial growth factor... Continue Reading
Nexavar® Added to Treatment Guidelines for Liver Cancer (March 8, 2009)Nexavar® Added to Treatment Guidelines for Liver Cancer The drug Nexavar® (sorafenib) has been added to the list of treatment options for patients with liver cancer who are not eligible for a liver transplant. This was reported in a recent presentation... Continue Reading
More Hepatocellular Carcinoma Liver CancerHighly Aggressive/High Grade Non-Hodgkin's Lymphoma
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)
Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology (March 8, 2009)New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology The 2008 ASH meeting featured several reports of new agents that are showing promise in the treatment of Non-Hodgkin’s... Continue Reading
More Highly Aggressive/High Grade Non-Hodgkin's LymphomaHIV Related Cancers
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
More HIV Related CancersHodgkin's Lymphoma
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Children with Favorable-Risk Hodgkin’s Lymphoma May Benefit from Limited Radiation Therapy (July 6, 2012)Children with favorable-risk Hodgkin’s lymphoma who achieve a complete early response to chemotherapy may not require radiation therapy or may undergo limited radiation therapy, according to the results of a study published in the Journal of the American... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Hodgkin's LymphomaHormonal Therapy
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More IIndolent/Low Grade Non-Hodgkin's Lymphoma
Fractionated Zevalin Effective First-Line Treatment for Advanced Follicular Lymphoma (February 8, 2013)
Fractionated radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is an effective first-line treatment for advanced stage follicular lymphoma and delivers high response rates in patients with high tumor burden, according to the results of... Continue Reading
Zevalin Effective as First-Line Treatment for Advanced Follicular Lymphoma (February 1, 2013)Radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is safe and well tolerated and induces a high rate of clinical and molecular responses when given as first-line treatment to patients with advanced stage follicular lymphoma, according... Continue Reading
Zevalin Effective in Follicular NHL Refractory to Rituximab (January 24, 2013)Radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is effective in patients with non-Hodgkin’s lymphoma that is refractory to treatment with Rituxan® (rituximab), according to the results of a study published in the Journal of Clinical... Continue Reading
Consolidation with Zevalin Significantly Improves Progression-Free Survival in Advanced Follicular Lymphoma (January 10, 2013)Consolidation therapy with Zevalin® (ibritumomab tiuxetan) significantly prolongs progression-free survival and leads to high conversion rates from partial response to complete response in patients with advanced follicular lymphoma, according to the... Continue Reading
Several Effective Treatment Options for Early Follicular Lymphoma (September 4, 2012)The results of a recent study published in the Journal of Clinical Oncology challenge the standard treatment approach for follicular lymphoma—indicating that with proper staging at diagnosis, there are several treatment regimens that can bring a remission. Non-Hodgkin’s... Continue Reading
More Indolent/Low Grade Non-Hodgkin's LymphomaInflammatory Breast Cancer
Radiation for Breast Cancer Increases Risk of Heart Disease and Heart Attack (March 27, 2013)
Exposure to ionizing radiation during radiation therapy for breast cancer may increase the risk of heart attack or heart disease later in life, according to the results of a study published in the New England Journal of Medicine. Many women with breast... Continue Reading
Increase in Number of Women Undergoing Reconstruction Immediately after Mastectomy (January 22, 2013)There has been a dramatic increase in the number of women undergoing immediate breast reconstruction after mastectomy—and this increase correlates with an increase in the use of implants, according to the results of a study published in Plastic and... Continue Reading
High Breast Density Does Not Increase Risk of Breast Cancer Death (August 29, 2012)Although high mammographic breast density is associated with an increased risk of developing cancer, it does not appear to increase the risk of death among breast cancer patients, according to the results of a study published in the Journal of the National... Continue Reading
Afinitor Approved for Advanced Breast Cancer (July 31, 2012)The U.S. Food and Drug Administration (FDA) has approved Afinitor® (everolimus) for use in combination with Aromasin® (exemestane) to treat postmenopausal women with advanced hormone-receptor positive, HER2-negative breast cancer. The combination is... Continue Reading
Physical Activity Linked to Reduced Mortality in Breast and Colon Cancer (May 22, 2012)Physical activity is associated with reduced mortality in patients with breast and colon cancer, according to a study published in the Journal of the National Cancer Institute.[1] So far, there is insufficient evidence to draw the same conclusion with... Continue Reading
More Inflammatory Breast CancerInfo Type
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More JK
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More LLeukemia
Ibrutinib Active In Untreated, Relapsed and Unresponsive CLL (June 3, 2013)
The drug ibrutinib was well tolerated and highly effective in patients with untreated, relapsed and unresponsive chronic lymphocytic leukemia—leading to large reductions in tumor burden, according to the results of a study presented at the American... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
CPX-351 Highly Active in Older Patients with AML (January 18, 2013)CPX-351 is highly active in all patient subgroups and produced the greatest benefits in response rate and reduction in 60-day mortality compared to standard therapy in older patients with secondary acute myeloid leukemia and adverse cytogenetics, according... Continue Reading
Combination of Revlimid and Vidaza Beneficial in Untreated Elderly Patients with AML (January 14, 2013)The sequential combination of Vidaza® (azacitidine) and Revlimid® (lenalidomide) shows evidence of clinical activity as initial therapy for older patients with acute myeloid leukemia, according to the results of a phase II study presented at the 54th... Continue Reading
More LeukemiaLimited Disease Lung Cancer - Small Cell
Prophylactic Cranial Irradiation May Improve Survival in Small Cell Lung Cancer (June 14, 2011)
Radiation to the brain prior to detectable spread of cancer to the brain improved survival in patients with both early- and late-stage small cell lung cancer. These results were recently presented at the 2011 meeting of the American Society of Clinical... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Smoking Cessation After Lung Cancer Diagnosis Improves Survival (February 11, 2010)Quitting smoking after a diagnosis of early-stage lung cancer may reduce the risk of cancer recurrence and death. These results were published in the British Medical Journal. Lung cancer is the leading cause of cancer death in the United States, with... Continue Reading
November Is National Lung Cancer Awareness Month (November 6, 2009)As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (July 22, 2009)Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published... Continue Reading
More Limited Disease Lung Cancer - Small CellLiver Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Statins Linked to Lower Risk of Liver Cancer in Hepatitis C (May 8, 2013)People infected with chronic hepatitis C are less likely to develop liver cancer if they are taking statins (cholesterol-lowering drugs), according to the results of a study published in the Journal of Clinical Oncology.[1] The liver is the largest organ... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Antiviral Therapy May Reduce the Risk of Tumor Recurrence in HBV-Related Liver Cancer (November 26, 2012)Patients with hepatitis B-related liver cancer who receive antiviral drugs after curative surgery have a lower risk of recurrence compared to those who do not receive antiviral therapy, according to the results of a study published in the Journal of the... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
More Liver CancerLocally Advanced Stage III (C) Prostate Cancer
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
Genomic Test May Help Guide Prostate Cancer Treatment (May 13, 2013)A new genetic test—the Oncotype DX® Prostate Cancer Test—measures the aggressiveness of prostate cancer and may help scores of men choose between immediate treatment or active surveillance. The test was shown to strongly predict aggressiveness of... Continue Reading
Early Radiation Improves Prostate Cancer Survival (March 7, 2013)Immediate radiation therapy after radical prostatectomy resulted in a 50 percent increase in long-term biochemical progression-free survival (bNED) in men with locally advanced prostate cancer, according to the results of a study presented at the Genitourinary... Continue Reading
No Difference in Toxicity Between Proton Therapy and IMRT for Prostate Cancer (January 28, 2013)Proton therapy does not reduce toxicity compared with intensity-modulated radiation therapy (IMRT) in men with prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute. Prostate cancer is the most... Continue Reading
Viagra Improves Sexual Function after Radiation for Prostate Cancer (November 15, 2012)Viagra® (sildenafil citrate) administered before, during, and after radiation therapy improved overall sexual function in prostate cancer patients, according to the results of a study presented at the 54th annual meeting of the American Society for... Continue Reading
More Locally Advanced Stage III (C) Prostate CancerLung Cancer
Standard Dose of Radiation Therapy Outperforms Higher Dose for Advanced Non-Small Cell Lung Cancer (June 12, 2013)
In a phase III clinical trial, a standard dose of radiation therapy was more effective than a higher dose for the treatment of stage III non-small cell lung cancer (NSCLC). These results will be presented at the 49th Annual Meeting of the American Society... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
More Lung CancerLung Cancer - Non-Small Cell
Standard Dose of Radiation Therapy Outperforms Higher Dose for Advanced Non-Small Cell Lung Cancer (June 12, 2013)
In a phase III clinical trial, a standard dose of radiation therapy was more effective than a higher dose for the treatment of stage III non-small cell lung cancer (NSCLC). These results will be presented at the 49th Annual Meeting of the American Society... Continue Reading
Ganetespib Promising for Advanced Lung Cancer (June 6, 2013)In a Phase II clinical trial, second-line treatment with a combination of chemotherapy and the investigational drug ganetespib improved overall survival among patients with advanced lung adenocarcinoma. These results were presented at the 2013 Annual... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
More Lung Cancer - Non-Small CellLung Cancer - Small Cell
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Diesel Exhaust Linked to Lung Cancer (June 26, 2012)Diesel exhaust is associated with an increased risk of lung cancer, according to a press release issued by the World Health Organization (WHO).[1] The announcement came after a group of international experts gathered for a weeklong meeting to review the... Continue Reading
More Lung Cancer - Small CellLymphoma
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Zevalin Effective in Follicular NHL Refractory to Rituximab (January 24, 2013)Radioimmunotherapy treatment with Zevalin® (ibritumomab tiuxetan) is effective in patients with non-Hodgkin’s lymphoma that is refractory to treatment with Rituxan® (rituximab), according to the results of a study published in the Journal of Clinical... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
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More MManagement and Prevention of Anemia Supportive Care
Exercise Reduces Chemotherapy-related Fatigue (October 21, 2009)
Exercise reduces fatigue and improves strength, physical functioning, and emotional well-being in men and women undergoing chemotherapy, according to the results of a study published in the British Medical Journal.[1] While exercise has long been associated... Continue Reading
More Management and Prevention of Anemia Supportive CareManagement and Prevention of Anorexia and Weight Loss Supportive Care
Fish Oil May Help Patients Maintain Weight During Chemotherapy (March 8, 2011)
Fish oil, taken as a dietary supplement, may help prevent muscle and weight loss among cancer patients who are undergoing chemotherapy. These findings were reported in the journal Cancer. Loss of muscle and weight is a potential side effect of chemotherapy... Continue Reading
More Management and Prevention of Anorexia and Weight Loss Supportive CareManagement and Prevention of Bone Complications Supportive Care
Xgeva Reduces Bone Complications From Prostate Cancer (February 25, 2011)
Among men with bone metastases from prostate cancer, Xgeva™ (denosumab) was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. Results from this Phase III clinical trial were published in The... Continue Reading
Xgeva Delays Bone Complications in Women with Metastatic Breast Cancer (December 21, 2010)In a study of women with bone metastases from breast cancer, Xgeva™ (denosumab) delayed bone complications for five months longer than Zometa® (zoledronic acid). These updated results from a Phase III clinical trial were presented at the 2010 San Antonio... Continue Reading
Denosumab Delays Bone Complications in Women with Metastatic Breast Cancer (November 23, 2010)Among women with bone metastases from breast cancer, denosumab may be more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. The results of this Phase III clinical trial were published in the Journal... Continue Reading
Denosumab More Effective Than Zometa at Delaying Bone Complications (October 15, 2010)Among patients with multiple myeloma or bone metastases from breast cancer, prostate cancer, or other solid tumors, denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. Results from... Continue Reading
Bisphosphonates May Provide Breast Cancer Benefits (December 11, 2009)Studies presented at the 2009 San Antonio Breast Cancer Symposium suggest that the class of bone drugs known as bisphosphonates may reduce the risk of breast cancer and may help to maintain bone density in breast cancer patients treated with aromatase... Continue Reading
More Management and Prevention of Bone Complications Supportive CareManagement and Prevention of Fatigue Supportive Care
Exercise Reduces Cancer-Related Fatigue (November 30, 2012)
Aerobic exercise can relieve the fatigue associated with cancer and its treatment, according to an updated systematic review published in The Cochrane Library. Fatigue is one of the most common side effects of cancer and its treatment. There are many... Continue Reading
Yoga Improves Sleep and Quality of Life (May 26, 2010)A four-week yoga program that included breathing, meditation, postures, and other techniques improved sleep and quality of life among cancer survivors. The results of this study will be presented at the 2010 annual meeting of the American Society of Clinical... Continue Reading
More Management and Prevention of Fatigue Supportive CareManagement and Prevention of Mucositis Supportive Care
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)
Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Oral Spray Reduces Mouth Sores (July 21, 2009)Among patients treated with radiation therapy for head and neck cancer, mouth sores (oral mucositis) were reduced by use of an oral spray containing epidermal growth factor (EGF). These results were published in Cancer. Mouth sores are one of the most... Continue Reading
More Management and Prevention of Mucositis Supportive CareManagement and Prevention of Nausea and Vomiting Supportive Care
Arrhythmia Risk Leads to Label Change for Zofran (July 9, 2012)
Interim data from a recent clinical trial has indicated that a 32 mg single dose of Zofran® (ondansetron) may affect the electrical activity of the heart and could predispose patients to develop an abnormal heart rhythm. The U.S. Food and Drug Administration... Continue Reading
Study Suggests Long-acting Patch that Prevents Nausea and Vomiting Can Be Given in Combination with Intravenous Medication (February 9, 2010)Use of a combination of Sancuso® (granisetron transdermal system; a patch that delivers granisetron through the skin for up to five days) and intravenous granisetron appears to be safe and feasible. This approach may provide immediate and extended... Continue Reading
More Management and Prevention of Nausea and Vomiting Supportive CareManagement and Prevention of Neutropenia Supportive Care
Neulasta Significantly Reduces Febrile Neutropenia Among Colorectal Cancer Patients Receiving Chemotherapy Plus Avasatin (February 25, 2013)
Neulasta® (pegfilgrastim) significantly reduced the incidence of grade 3/4 febrile neutropenia among patients with locally advanced or metastatic colorectal cancer who received chemotherapy with FOLFOX or FOLFIRI followed by Avastin® (bevacizumab),... Continue Reading
Naproxen May Relieve Bone Pain Associated with Neulasta (August 2, 2012)Twice-daily naproxen is effective in reducing the incidence and severity of bone pain associated with the use of Neulasta® (pegfilgrastim), according to the results of a study published in the Journal of Clinical Oncology. Neulasta is a blood cell growth... Continue Reading
Celebrities Stand Up to Cancer (September 14, 2009)Celebrities and Amgen are joining forces to Stand Up to Cancer™—in the form of a public service campaign designed to educate cancer patients and caregivers about managing the increased risk of infection during cancer treatment. Chemotherapy is an... Continue Reading
Amgen Helps Reduce Out-of-pocket Costs for Neulasta® (July 3, 2009)Amgen’s Neulasta FIRST STEP™ Program provides assistance to eligible, low-income, commercially-insured chemotherapy patients who need help with their co-insurance or co-payment requirement for Neulasta® (pegfilgrastim). Neulasta is a blood cell growth... Continue Reading
More Management and Prevention of Neutropenia Supportive CareManagement and Prevention of Thrombocytopenia Supportive Care
Nplate Produces Rapid Response in Adults with ITP (December 20, 2011)
Among adults with low platelet counts or bleeding symptoms from primary immune thrombocytopenia (ITP), treatment with Nplate® (romiplostim) produces a rapid increase in platelet counts. These results were presented at the 53rd Annual Meeting of the American... Continue Reading
Nplate Active for More than Five Years in Adults with Chronic ITP (December 13, 2010)Nplate® (romiplostim) appears to maintain platelet counts among adult patients with chronic immune (idiopathic) thrombocytopenia purpura (ITP) for more than five years. These results were presented at the 52nd Annual Meeting and Exposition of the American... Continue Reading
Nplate Reduces Treatment Failure and Splenectomy in Patients with ITP (November 17, 2010)Compared with standard therapies, Nplate® (romiplostim) appears to reduce the risk of treatment failure and need for splenectomy among adult patients with chronic immune thrombocytopenia (ITP). These results were published in the New England Journal... Continue Reading
Nplate Evaluated in Children with Chronic ITP (December 9, 2009)Among children with chronic immune thrombocytopenic purpura (ITP; an autoimmune disorder characterized by low platelet counts), treatment with Nplate® (romiplostim) stimulates platelet production and appears to be well tolerated. These results were presented... Continue Reading
More Management and Prevention of Thrombocytopenia Supportive CareMantle Cell Non-Hodgkin's Lymphoma
R-CHOP Induction Plus Rituxan Maintenance Improves Remission in Older Patients with Mantle Cell Lymphoma (October 23, 2012)
Induction therapy with R-CHOP followed by maintenance with Rituxan® (rituximab) nearly doubled the remission duration in older patients with mantle cell lymphoma, according to the results of a study published in the New England Journal of Medicine. Non-Hodgkin’s... Continue Reading
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
More Mantle Cell Non-Hodgkin's LymphomaMelanoma
Immunotherapy Combination Promising for Metastatic Melanoma (June 14, 2013)
For people with metastatic melanoma, treatment with a combination of Yervoy® (ipilimumab) and Leukine® (sargramostim; GM-CSF) may result in better overall survival than treatment with Yervoy alone. These results, from a Phase II clinical trial, were... Continue Reading
Intermittent Zelboraf Treatment in Patients with Melanoma May Prevent Resistance to the Drug (May 22, 2013)Tumors resistant to Zelboraf® (vemurafenib) in patients with melanoma showed reduced growth after treatment was stopped. What’s more—animal models have shown that drug resistance was prevented by intermittent treatment. These results were presented... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Lymphoseek Approved for Detecting Lymph Nodes in Breast Cancer and Melanoma (April 10, 2013)The U.S. Food and Drug Administration (FDA) has approved Lymphoseek® (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing... Continue Reading
Aspirin Reduces Risk of Melanoma in Women (March 20, 2013)Women who regularly take aspirin have a reduced risk of developing melanoma, according to the results of a study published in Cancer.[1] What’s more—the longer they take the aspirin, the lower the risk. Of the more than one million new diagnoses of... Continue Reading
More MelanomaMesothelioma
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
More MesotheliomaMetastatic Breast Cancer
Genomic Testing with Oncotype DX Provides Prognostic Information in Stage IV Breast Cancer (June 4, 2013)
Among women with Stage IV, estrogen receptor-positive breast cancer, the Oncotype DX® breast cancer test provided information about cancer prognosis; this may help guide treatment decisions. These results were presented at the 2013 Annual Meeting of... Continue Reading
Biomarker Analysis Identifies Women Most Likely to Benefit From Kadcyla (May 20, 2013)Among women with metastatic, HER2-positive breast cancer, those with the highest tumor HER2 levels benefit the most from the drug Kadcyla™ (ado-trastuzumab emtansine, formerly known as T-DM1), according to the results of a study presented at the American... Continue Reading
Radiation for Breast Cancer Increases Risk of Heart Disease and Heart Attack (March 27, 2013)Exposure to ionizing radiation during radiation therapy for breast cancer may increase the risk of heart attack or heart disease later in life, according to the results of a study published in the New England Journal of Medicine. Many women with breast... Continue Reading
Kadcyla Approved for HER2-Positive Metastatic Breast Cancer (March 19, 2013)The U.S. Food and Drug Administration (FDA) has approved Kadcyla™ (ado-trastuzumab emtansine, formerly known as T-DM1) for the treatment of HER2-positive, metastatic breast cancer that has been previously treated with Herceptin® (trastuzumab) and taxanes,... Continue Reading
Copper Depletion May Reduce Spread of Triple-Negative Breast Cancer (March 4, 2013)In a Phase II clinical trial, an anti-copper drug has shown promising results against triple-negative breast cancer. These results were published in the Annals of Oncology. Studies have suggested that bone marrow cells known as endothelial progenitor... Continue Reading
More Metastatic Breast CancerMetastatic Stage IV (D) Prostate Cancer
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
FDA Approves Xofigo for Advanced Prostate Cancer (June 17, 2013)The U.S. Food and Drug Administration (FDA) has approved Xofigo® (radium Ra 223 dichloride) to treat men with metastatic, hormone-refractory prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread... Continue Reading
Genomic Test May Help Guide Prostate Cancer Treatment (May 13, 2013)A new genetic test—the Oncotype DX® Prostate Cancer Test—measures the aggressiveness of prostate cancer and may help scores of men choose between immediate treatment or active surveillance. The test was shown to strongly predict aggressiveness of... Continue Reading
No Difference in Toxicity Between Proton Therapy and IMRT for Prostate Cancer (January 28, 2013)Proton therapy does not reduce toxicity compared with intensity-modulated radiation therapy (IMRT) in men with prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute. Prostate cancer is the most... Continue Reading
Zytiga Approval Expanded (December 17, 2012)The U.S. Food and Drug Administration (FDA) has expanded the approved use of Zytiga® (abiraterone) to treat men with metastatic, hormone-refractory prostate cancer prior to receiving chemotherapy. Prostate cancer is a hormonally sensitive disease that... Continue Reading
More Metastatic Stage IV (D) Prostate CancerMetastatic/Stage IVB Cervical Cancer
Avastin Improves Outcomes for Women with Advanced Cervical Cancer (June 11, 2013)
In a Phase III clinical trial, adding Avastin® (bevacizumab) to chemotherapy prolonged overall survival among women with recurrent or metastatic cervical cancer. These results were presented at the 2013 Annual Meeting of the American Society of Clinical... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Metastatic/Stage IVB Cervical CancerMiscellaneous
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)
Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
More MiscellaneousMultiple Myeloma
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Pomalyst Approved for Advanced Multiple Myeloma (March 13, 2013)The U.S. Food and Drug Administration (FDA) has approved Pomalyst® (pomalidomide) for the treatment of patients with multiple myeloma whose disease progressed after being treated with other cancer drugs. Multiple myeloma is a cancer of plasma cells,... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Zevalin Effective in Relapsed/Refractory Follicular Lymphoma (January 11, 2013)Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
Pomalidomide Improves Survival in Refractory Multiple Myeloma (January 8, 2013)Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
More Multiple MyelomaMyelodysplastic Syndrome
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
More Myelodysplastic SyndromeN
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More NNeuroblastoma
Cancer Deaths on the Decline (February 11, 2013)
Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Targeted Agent Xalkori May Benefit Children with Anaplastic Lymphoma (May 23, 2012)The targeted agent Xalkori® (crizotinib) appears to drastically reduce the size of tumors in children with refractory anaplastic large cell lymphoma, according to the results of a phase I study that will be presented at the annual meeting of the American... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
More NeuroblastomaNews
Some Squamous Cell Skin Cancers Are Deadly (June 19, 2013)
Cutaneous squamous cell carcinoma is usually easily treated with surgery; however, a subsection of patients with specific disease risk factors are more likely to develop metastases and die from the disease, according to the results of a study published... Continue Reading
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
Oncotype DX® Predicts Recurrence in Patients with DCIS (June 18, 2013)The Oncotype DX® DCIS Score predicts the 10-year risk of local recurrence, defined as recurrence of DCIS or invasive breast cancer in the same breast, and can help guide radiation treatment decision-making for women with DCIS who are treated with breast-conserving... Continue Reading
FDA Approves Xofigo for Advanced Prostate Cancer (June 17, 2013)The U.S. Food and Drug Administration (FDA) has approved Xofigo® (radium Ra 223 dichloride) to treat men with metastatic, hormone-refractory prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread... Continue Reading
Genomic Testing May Reduce Medical Costs for Colon Cancer (June 14, 2013)Use of the Oncotype DX® colon cancer test to guide treatment decisions may reduce medical costs and improve patient well-being. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). The Oncotype... Continue Reading
More NewsNon-Hodgkin's Lymphoma
Rituxan May Prevent Need for Radiation in Mediastinal B-Cell Lymphoma (May 31, 2013)
A dose-adjusted, infusion approach to aggressive chemotherapy with Rituxan® (rituximab) may allow patients with primary mediastinal B-cell lymphoma to skip radiation, according to the results of a study published in the New England Journal of Medicine. Non-Hodgkin’s... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
RIT Conditioning with Zevalin Prior to Autologous Transplantation Improves Overall Survival in Patients with DLCL (April 5, 2013)Radioimmunotherapy conditioning with Zevalin® (ibritumomab tiuxetan) prior to autologous stem cell transplantation in patients with diffuse large cell lymphoma offers a similar relapse incidence to total body irradiation, but has lower toxicity and improved... Continue Reading
Treanda Plus Rituxan is Not Inferior to R-CHOP and R-CVP for advanced NHL (April 2, 2013)The combination of Treanda® (bendamustine) and Rituxan® (rituximab) was found to be noninferior to the commonly used chemotherapy regimens R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) and R-CVP (rituximab plus cyclophosphamide,... Continue Reading
Zevalin Plus Nonmyeloablative Allogeneic Transplantation Effective in High-Risk B-Cell NHL (March 29, 2013)The addition of Zevalin® (ibritumomab tiuxetan) to nonmyeloablative allogeneic transplantation (NMAT) is safe and produces early responses and prolonged disease control in high-risk patients with B-cell non-Hodgkin’s lymphoma, according to the results... Continue Reading
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Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)
Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
Clinical Trial Participation Is Inadequate (August 31, 2011)A large proportion of cancer patients do not enroll in clinical trials, and those who do participate may not adequately represent age groups, cancer stages, cancer types, and racial and ethnic groups. These findings were recently reported in the Annals... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Survivors of Childhood Cancer Face Risk of More Cancer (July 11, 2011)Children who survive cancer have an increased risk of developing cancer later in life. These findings were recently reported in the Journal of Clinical Oncology. The good news about childhood cancer is that increasingly more children are surviving. These... Continue Reading
More OsteosarcomaOther News Topics (not Types of Cancer)
Number of Cancer Survivors Expected to Reach 18 Million by 2022 (May 1, 2013)
As of January 2012, there were approximately 13.7 million cancer survivors in the United States and that number is expected to rise by 31 percent to 18 million by 2022, according to the second Annual Report on Cancer Survivorship in the United States published... Continue Reading
Heart Healthy Lifestyle Can Reduce Cancer Risk (April 19, 2013)Following a heart-healthy lifestyle to reduce the risk for heart disease can also help prevent cancer, according to the results of a study published in Circulation. The American Heart Association designed their educational program My Life Check® in order... Continue Reading
Mutation in Immortality Gene Linked to Brain and Other Tumors (April 17, 2013)Newly identified mutations in a gene that makes cells immortal—the TERT promoter gene—appear to play a role in several types of cancer, including three of the most common types of brain tumors, according to the results of a study published in the... Continue Reading
Exercise Reduces Cancer-Related Fatigue (November 30, 2012)Aerobic exercise can relieve the fatigue associated with cancer and its treatment, according to an updated systematic review published in The Cochrane Library. Fatigue is one of the most common side effects of cancer and its treatment. There are many... Continue Reading
U.S. Will Cover Cancer Treatment for 9/11 Responders (September 20, 2012)The National Institute for Occupational Safety and Health has announced that responders and survivors exposed to toxic compounds from the 9/11 wreckage at the World Trade Center (WTC) and the Pentagon are entitled to free monitoring and treatment for... Continue Reading
More Other News Topics (not Types of Cancer)Ovarian Cancer
Maintenance Therapy with Votrient Provides Benefit in Advanced Ovarian Cancer (June 13, 2013)
In a Phase III clinical trial, treatment with Votrient® (pazopanib) after initial chemotherapy improved outcomes among women with advanced ovarian cancer. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology... Continue Reading
Novel Two-step Immunotherapy Shows Promise in Recurrent Ovarian Cancer (May 17, 2013)A novel two-step immunotherapy approach yielded clinically beneficial responses in patients with advanced ovarian cancer, according to data from two phase I clinical trials presented at the American Association for Cancer Research (AACR) Annual Meeting... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Delaying Chemotherapy Increases Mortality in Ovarian Cancer (April 12, 2013)Women with advanced ovarian cancer have significantly worse survival when they wait more than 25 days after surgery to start chemotherapy, according to the results of a study presented at the 2013 Society of Gynecologic Oncology Annual Meeting on Women’s... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
More Ovarian CancerP
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More PPain Management Supportive Care
Antidepressant Cymbalta May Reduce Pain from Chemotherapy-Induced Peripheral Neuropathy (May 24, 2013)
The antidepressant Cymbalta® (duloxetine) appears to reduce the numbness and tingling associated with taxane or platinum-based chemotherapy, according to the results of a study published in the Journal of the American Medical Association. Peripheral... Continue Reading
Acupuncture Relieves Pain, Improves Functioning After Neck Surgery (April 28, 2010)Acupuncture may reduce pain and improve functioning among patients with cancer who have undergone surgery to the neck, according to a study published in the Journal of Clinical Oncology.[1] As well, acupuncture may relieve xerostomia (dry mouth) among... Continue Reading
Onsolis Approved for Breakthrough Pain (July 28, 2009)Onsolis (fentanyl buccal soluble film) has been approved by the U.S. Food and Drug Administration for the treatment of breakthrough cancer pain.[1] Pain may be a side effect of cancer treatment or may be caused by the cancer itself. If not adequately... Continue Reading
More Pain Management Supportive CarePancreatic Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Abraxane Improves Survival in Pancreatic Cancer (February 13, 2013)Abraxane® (nab-paclitaxel) prolonged life in patients with metastatic pancreatic cancer by an average of two months longer than chemotherapy and significantly increased the percentage of patients who survived for up to two years, according to the results... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Pancreatic CancerProgressive Relapsed Hodgkin's Lymphoma
Adcetris Approved for Two Types of Lymphoma (August 26, 2011)
The targeted therapy Adcetris™ (brentuximab vedotin) has received accelerated approved by the US Food and Drug Administration (FDA) for the treatment of two types of lymphoma: Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL). Hodgkin... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Targeted Therapy Promising for Relapsed Hodgkin Lymphoma (January 12, 2011)In a Phase II clinical trial, three-quarters of patients with relapsed or refractory Hodgkin lymphoma responded to treatment with the investigational drug brentuximab vedotin. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Panobinostat Promising in Relapsed/Refractory Hodgkin’s Lymphoma (November 9, 2010)An ongoing study of the experimental drug panobinostat (LBH-589) reports promising activity in heavily pretreated patients with relapsed and refractory Hodgkin’s lymphoma (HL). These findings were presented at the 2010 annual meeting of the American... Continue Reading
Allogeneic Stem Cell Transplantation Viable for Children and Adolescents with Relapsed Hodgkin’s Lymphoma (September 24, 2009)Children and adolescents with relapsed Hodgkin’s lymphoma respond well to allogeneic stem cell transplantation, according to the results of a study published in Blood.[1] Although children and adolescents with Hodgkin’s lymphoma have an excellent... Continue Reading
More Progressive Relapsed Hodgkin's LymphomaProstate Cancer
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
FDA Approves Xofigo for Advanced Prostate Cancer (June 17, 2013)The U.S. Food and Drug Administration (FDA) has approved Xofigo® (radium Ra 223 dichloride) to treat men with metastatic, hormone-refractory prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread... Continue Reading
Study Compares Genomic Testing of Normal and Cancerous Prostate Tissue (June 12, 2013)The Oncotype DX® prostate cancer test—which predicts the aggressiveness of early-stage prostate cancer and may help guide treatment decisions—is more predictive of outcome when used on tumor tissue than when used on adjacent, normal prostate tissue.... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Genomic Test May Help Guide Prostate Cancer Treatment (May 13, 2013)A new genetic test—the Oncotype DX® Prostate Cancer Test—measures the aggressiveness of prostate cancer and may help scores of men choose between immediate treatment or active surveillance. The test was shown to strongly predict aggressiveness of... Continue Reading
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More RadiopharmaceuticalRectal Cancer
Erbitux Plus Chemo Boosts Survival in Patients with Colorectal Cancer and Liver Metastases (May 29, 2013)
Adding Erbitux® (cetuximab) to standard chemotherapy might allow some patients with colorectal cancer and inoperable liver metastases to undergo successful surgical resection of the liver metastasis, according to the results of a study published in the Journal... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
New Colonoscopy Surveillance Guidelines (October 10, 2012)The U.S. Multi-Society Task Force on Colorectal Cancer has released a consensus update regarding colonoscopy surveillance—and the guidelines indicate that average-risk patients who have a clean colonoscopy can wait 10 years between exams. Colorectal... Continue Reading
More Rectal CancerRecurrent Anal Cancer
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)
Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
More Recurrent Anal CancerRecurrent Bladder Cancer
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)
Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Cystoscopy Alone Is the Most Cost-effective Way to Monitor for Recurrence of Bladder Cancer (March 9, 2010)The addition of a urine test to standard cystoscopy screening in order to monitor for bladder cancer recurrence unnecessarily increases the cost of monitoring as well as the risk for a false-positive result and does not improve tumor detection, according... Continue Reading
More Recurrent Bladder CancerRecurrent Breast Cancer
Radiation for Breast Cancer Increases Risk of Heart Disease and Heart Attack (March 27, 2013)
Exposure to ionizing radiation during radiation therapy for breast cancer may increase the risk of heart attack or heart disease later in life, according to the results of a study published in the New England Journal of Medicine. Many women with breast... Continue Reading
Kadcyla Approved for HER2-Positive Metastatic Breast Cancer (March 19, 2013)The U.S. Food and Drug Administration (FDA) has approved Kadcyla™ (ado-trastuzumab emtansine, formerly known as T-DM1) for the treatment of HER2-positive, metastatic breast cancer that has been previously treated with Herceptin® (trastuzumab) and taxanes,... Continue Reading
Increase in Number of Women Undergoing Reconstruction Immediately after Mastectomy (January 22, 2013)There has been a dramatic increase in the number of women undergoing immediate breast reconstruction after mastectomy—and this increase correlates with an increase in the use of implants, according to the results of a study published in Plastic and... Continue Reading
Investigational Agent Demonstrates Benefit in Advanced ER-Positive Breast Cancer (December 12, 2012)The combination of Femara® (letrozole) and the investigational agent PD 0332991 significantly improved median progression-free survival in patients with advanced estrogen receptor-positive (ER-positive) breast cancer, according to the results of a study... Continue Reading
Some Evidence of Mild “Chemo Brain” in Breast Cancer Survivors (September 14, 2012)Breast cancer patients treated with chemotherapy are at risk for mild cognitive deficits (sometimes referred to as chemo brain) after treatment, according to the results of a study published early online in the Journal of Clinical Oncology. A large portion... Continue Reading
More Recurrent Breast CancerRecurrent Cervical Cancer
Avastin Improves Outcomes for Women with Advanced Cervical Cancer (June 11, 2013)
In a Phase III clinical trial, adding Avastin® (bevacizumab) to chemotherapy prolonged overall survival among women with recurrent or metastatic cervical cancer. These results were presented at the 2013 Annual Meeting of the American Society of Clinical... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Avastin® Shows Promise in Treatment of Cervical Cancer (March 8, 2009)Avastin® Shows Promise in Treatment of Cervical Cancer According to the results of a Phase II clinical trial, the targeted therapy Avastin® (bevacizumab) warrants further investigation in the treatment of persistent or recurrent squamous cell carcinoma... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers (March 8, 2009)Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers The administration of the blood cell growth factor Neulasta® (pegfilgrastim) on the first day of chemotherapy among women with gynecologic cancers may be as effective... Continue Reading
More Recurrent Cervical CancerRecurrent Gastric Cancer
Second-Line Docetaxel Improves Survival in Esophageal and Gastric Cancer (April 3, 2013)
Second-line treatment with docetaxel improves overall survival of patients with advanced esophageal and gastric cancer, according to the results of a study presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco. The esophagus is a muscular... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Herceptin® Approved for HER2-positive Metastatic Stomach Cancer (November 2, 2010)The U.S. Food and Drug Administration (FDA) has expanded the approval of Herceptin® (trastuzumab) to include the initial treatment of HER2-positive metastatic cancer of the stomach or gastroesophageal junction in combination with chemotherapy.[1] Herceptin... Continue Reading
Clinical Trial for Advanced Gastric Cancer Now Enrolling Patients (July 16, 2010)Gastric cancer forms in the tissues and lining of the stomach. Current treatment options include surgery, chemotherapy, and radiation. The current standard of care for metastatic gastric cancer is systemic therapy. Research is ongoing to determine which... Continue Reading
Herceptin® Improves Survival with HER2-positive Gastric Cancer (June 2, 2009)Herceptin® Improves Survival with HER2-positive Gastric Cancer According to the results of a Phase III clinical trial presented at the 2009 annual meeting of the American Society of Clinical Oncology (ASCO), treatment with a combination of chemotherapy... Continue Reading
More Recurrent Gastric CancerRecurrent Liver Cancer
Cabozantinib Shows Promise against Bone Metastases (May 31, 2011)
The investigational drug cabozantinib is showing promise against several types of advanced cancer, and may also reduce or eliminate bone metastases (cancer that has spread to the bone) in some patients. These results will be presented at the 2011 annual... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
More Recurrent Liver CancerRecurrent Lung Cancer - Non-Small Cell
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)
Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Xalkori Superior to Standard Chemotherapy in ALK-Positive Lung Cancer (October 4, 2012)The targeted therapy Xalkori® (crizotinib) is superior to standard chemotherapy for the treatment of patients with advanced, ALK-positive non-small cell lung cancer, according to the results of a phase III trial presented at the ESMO 2012 Congress of... Continue Reading
Genetic Study Identifies New Targets for Treating Squamous Cell Lung Cancer (September 19, 2012)Researchers have identified a large variety of genetic alterations that appear to be responsible for the development and growth of squamous cell lung cancer, according to the results of a study published in Nature. The discovery could lead to new targeted... Continue Reading
Two Studies Show Promise in Second-Line Treatments for NSCLC (August 14, 2012)Two studies presented at the 2012 annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Illinois shed new light on the best way to treat non-small cell lung cancer (NSCLC)—one indicating that chemotherapy may be superior to... Continue Reading
PD-1 Targeted Immune Therapy Shows Promising Activity (June 11, 2012)The investigational drug BMS-936558 caused tumor shrinkage in nearly 25 percent of patients with advanced melanoma, kidney cancer and non-small cell lung cancer (NSCLC), according to the results of a phase I study presented at the 2012 annual meeting... Continue Reading
More Recurrent Lung Cancer - Non-Small CellRecurrent Lung Cancer - Small Cell
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)
Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
November Is National Lung Cancer Awareness Month (November 6, 2009)As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
More Recurrent Lung Cancer - Small CellRecurrent Melanoma
Intermittent Zelboraf Treatment in Patients with Melanoma May Prevent Resistance to the Drug (May 22, 2013)
Tumors resistant to Zelboraf® (vemurafenib) in patients with melanoma showed reduced growth after treatment was stopped. What’s more—animal models have shown that drug resistance was prevented by intermittent treatment. These results were presented... Continue Reading
Combined Targeted Therapy Safe and Effective in Metastatic Melanoma (October 24, 2012)Treatment with a combination of two targeted agents—dabrafenib, which targets BRAF, and trametinib, which targets MEK—in patients with metastatic melanoma and BRAF V600 mutations was safe and improved progression-free survival, according to the results... Continue Reading
Adjuvant Radiotherapy for the Management of High-Risk Malignant Melanoma (September 24, 2012)Adjuvant radiotherapy significantly improved regional lymphatic control for high-risk patients after therapeutic lymphadenectomy for metastatic melanoma, according to the results of a study published in the Lancet Oncology. Of the more than one million... Continue Reading
PD-1 Targeted Immune Therapy Shows Promising Activity (June 11, 2012)The investigational drug BMS-936558 caused tumor shrinkage in nearly 25 percent of patients with advanced melanoma, kidney cancer and non-small cell lung cancer (NSCLC), according to the results of a phase I study presented at the 2012 annual meeting... Continue Reading
Zelboraf Improves Melanoma Survival (March 16, 2012)Among patients with previously treated metastatic melanoma that carries a certain gene mutation, the targeted drug Zelboraf® (vemurafenib) resulted in a median overall survival of 16 months. This is a substantial improvement over what has been seen in... Continue Reading
More Recurrent MelanomaRecurrent Multiple Myeloma
Pomalyst Approved for Advanced Multiple Myeloma (March 13, 2013)
The U.S. Food and Drug Administration (FDA) has approved Pomalyst® (pomalidomide) for the treatment of patients with multiple myeloma whose disease progressed after being treated with other cancer drugs. Multiple myeloma is a cancer of plasma cells,... Continue Reading
Zevalin Effective in Relapsed/Refractory Follicular Lymphoma (January 11, 2013)Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
Pomalidomide Improves Survival in Refractory Multiple Myeloma (January 8, 2013)Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
MLN9708 “Oral Velcade” Shows Promise in Multiple Myeloma (January 3, 2013)The investigational, oral proteasome inhibitor MLN9708, which is a new version of Velcade® (bortezomib)—may be more effective and better tolerated than the Velcade injections, according to data from a mid-stage study presented at the 54th Annual Meeting... Continue Reading
Kyprolis Approved for Multiple Myeloma (July 24, 2012)The U.S. Food and Drug Administration (FDA) has approved Kyprolis™ (carfilzomib) for the treatment of patients with multiple myeloma that has already been treated with at least two prior therapies—including Velcade® (bortezomib) and a drug such as... Continue Reading
More Recurrent Multiple MyelomaRecurrent Non-Hodgkin's Lymphoma
Adcetris Approved for Two Types of Lymphoma (August 26, 2011)
The targeted therapy Adcetris™ (brentuximab vedotin) has received accelerated approved by the US Food and Drug Administration (FDA) for the treatment of two types of lymphoma: Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL). Hodgkin... Continue Reading
Brentuximab Vedotin Effective for Patients with Relapsed or Refractory Anaplastic Large Cell Lymphoma (June 16, 2011)Researchers involved in an international multicenter trial have reported that brentuximab vedotin was effective for treatment of patients with relapsed or refractory anaplastic large cell lymphoma. The details of this study were reported at the 2011 meeting... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
More Recurrent Non-Hodgkin's LymphomaRecurrent Ovarian Cancer
Novel Two-step Immunotherapy Shows Promise in Recurrent Ovarian Cancer (May 17, 2013)
A novel two-step immunotherapy approach yielded clinically beneficial responses in patients with advanced ovarian cancer, according to data from two phase I clinical trials presented at the American Association for Cancer Research (AACR) Annual Meeting... Continue Reading
Ovarian Cancer Rates Declining in Breast Cancer Survivors (February 7, 2013)The rate of second primary ovarian cancers after first primary breast cancer appears to be on the decline, according to the results of a study published in the Journal of Clinical Oncology. Each year in the United States, roughly 22,000 women are diagnosed... Continue Reading
Diabetes Drug May Help Prevent or Treat Ovarian Cancer (December 3, 2012)Metformin, a widely prescribed insulin-lowering drug for diabetes, has been associated with survival in ovarian cancer and is worthy of further study, as it may be considered for the prevention or treatment of ovarian cancer, according to the results... Continue Reading
Treatment at High-Volume Hospitals Leads to Lower Mortality Rates for Ovarian Patients (November 20, 2012)Ovarian cancer patients who undergo surgery at high-volume hospitals have better outcomes than those who are treated at low-volume hospitals, according to the results of a study published in the Journal of Clinical Oncology. This is the result not of... Continue Reading
Gene Helps Predict Response to Chemotherapy in Ovarian Cancer (September 28, 2012)Measuring the activity of a gene called FGF1 could help predict which women with ovarian cancer will benefit from platinum-based chemotherapy, according to the results of a study published in the British Journal of Cancer. Each year in the United States,... Continue Reading
More Recurrent Ovarian CancerRecurrent Pancreatic Cancer
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)
Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
November Is National Pancreatic Cancer Awareness Month (November 5, 2009)As the month of November brings pancreatic cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated pancreatic... Continue Reading
More Recurrent Pancreatic CancerRecurrent Testicular Cancer
Marijuana May Increase Risk of Testicular Cancer (September 21, 2012)
Recreational marijuana use may increase the risk of developing subtypes of testicular cancer that have a worse prognosis, according to the results of a study published early online in the journal Cancer. Testicular cancer is the most common cancer diagnosed... Continue Reading
Paclitaxel/Gemzar Provides Long-Term Survival in Refractory Testicular Cancer (June 14, 2011)Treatment with the chemotherapy agents paclitaxel and Gemzar® (gemcitabine) provides long-term survival and possible cure among some patients with testicular cancer that has stopped responding to prior therapies. These results were recently presented... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
More Recurrent Testicular CancerRecurrent Uterine Cancer
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)
Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers (March 8, 2009)Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers The administration of the blood cell growth factor Neulasta® (pegfilgrastim) on the first day of chemotherapy among women with gynecologic cancers may be as effective... Continue Reading
More Recurrent Uterine CancerRecurrent/Relapsed Rectal Cancer
Erbitux Plus Chemo Boosts Survival in Patients with Colorectal Cancer and Liver Metastases (May 29, 2013)
Adding Erbitux® (cetuximab) to standard chemotherapy might allow some patients with colorectal cancer and inoperable liver metastases to undergo successful surgical resection of the liver metastasis, according to the results of a study published in the Journal... Continue Reading
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Zaltrap Approved for Metastatic Colorectal Cancer (August 15, 2012)The U.S. Food and Drug Administration (FDA) has approved Zaltrap® (ziv-aflibercept) for use in combination with the FOLFIRI chemotherapy regimen (folinic acid, fluorouracil, and ironotecan) to treat adults with metastatic colorectal cancer. Colorectal... Continue Reading
Regorafenib Shows Promise Against Metastatic Colorectal Cancer (January 19, 2012)The investigational drug regorafenib improves survival and delays cancer progression among patients with metastatic colorectal cancer that has worsened in spite of other treatments. These results will be presented at the 2012 Gastrointestinal Cancers... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
More Recurrent/Relapsed Rectal CancerRefactory/Recurrent Prostate Cancer
ASTRO and AUA Issue Joint Guideline for Radiation After Prostate Surgery (June 19, 2013)
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) have issued a joint guideline regarding the use of radiation therapy after prostatectomy. It marks the first time the two medical organizations—most responsible... Continue Reading
FDA Approves Xofigo for Advanced Prostate Cancer (June 17, 2013)The U.S. Food and Drug Administration (FDA) has approved Xofigo® (radium Ra 223 dichloride) to treat men with metastatic, hormone-refractory prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread... Continue Reading
Genomic Test May Help Guide Prostate Cancer Treatment (May 13, 2013)A new genetic test—the Oncotype DX® Prostate Cancer Test—measures the aggressiveness of prostate cancer and may help scores of men choose between immediate treatment or active surveillance. The test was shown to strongly predict aggressiveness of... Continue Reading
No Difference in Toxicity Between Proton Therapy and IMRT for Prostate Cancer (January 28, 2013)Proton therapy does not reduce toxicity compared with intensity-modulated radiation therapy (IMRT) in men with prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute. Prostate cancer is the most... Continue Reading
Intermittent and Continuous Hormone Therapy are Equally Effective in Prostate Cancer Treatment (September 18, 2012)Hormone therapy given intermittently (with breaks) has proven to be as effective as hormone therapy given continuously in asymptomatic men with rising PSA levels after prostate cancer treatment, according to the results of a study published in the New... Continue Reading
More Refactory/Recurrent Prostate CancerRenal Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
New Treatment Options for Advanced Renal Cell Carcinoma (October 8, 2012)The results from three phase III trials shed new light on treatment options for patients with advanced renal cell carcinoma. The studies were presented at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna. More than 58,000... Continue Reading
PD-1 Targeted Immune Therapy Shows Promising Activity (June 11, 2012)The investigational drug BMS-936558 caused tumor shrinkage in nearly 25 percent of patients with advanced melanoma, kidney cancer and non-small cell lung cancer (NSCLC), according to the results of a phase I study presented at the 2012 annual meeting... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
More Renal CancerRetinoblastoma
Cancer Deaths on the Decline (February 11, 2013)
Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
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Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Shorter Chemotherapy Intervals Effective in Ewing Sarcoma (November 1, 2012)In patients with localized Ewing sarcoma, chemotherapy administered every two weeks is more effective than chemotherapy administered every three weeks, with no increase in toxicity, according to the results of a study published in the Journal of Clinical... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More SarcomaScreening/Prevention Anal Cancer
Anal Cancer Rates Appear to Be On the Rise in the U.S. (May 6, 2013)
The number of people in the United States with anal cancer has tripled since the 1970s, according to the results of a study published in the Journal of Clinical Oncology. Anal cancer is an uncommon type of cancer that occurs in the anal canal, the opening... Continue Reading
Anal Cancer on the Rise in Men with HIV (October 15, 2012)Nearly one-third of men with anal cancer have the human immunodeficiency virus (HIV), according to the results of a study published in the Journal of the National Cancer Institute. Anal cancer is an uncommon type of cancer that occurs in the anal canal,... Continue Reading
HPV Vaccine Reducing Infection among Vaccinated and Unvaccinated (July 16, 2012)The human papillomavirus (HPV) vaccine is reducing infections of virus strains associated with genital warts and cancer, even among those who remain unvaccinated, according to the results of a study published in Pediatrics. HPV is the most common sexually... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
HPV Vaccine May Prevent Anal Cancer (September 14, 2011)Cervarix® (human papillomavirus bivalent [types 16 and 18] recombinant vaccine), an FDA-approved vaccine for the prevention of cervical cancer, may also help prevent anal cancer. These findings were recently reported in Lancet Oncology. Human papillomaviruses... Continue Reading
More Screening/Prevention Anal CancerScreening/Prevention Bladder Cancer
More Evidence that Diabetes Drugs Increase Risk of Bladder Cancer (August 22, 2012)
A popular class of diabetes drugs called thiazolidinediones (TZDs) increases the risk of bladder cancer, according to the results of a study published early online in the Journal of the National Cancer Institute. Bladder cancer is diagnosed in as many... Continue Reading
Diabetes Drugs May Increase Risk of Bladder Cancer (July 26, 2012)A class of drugs called thiazolidinediones has been linked to an increased risk of bladder cancer among adults with type 2 diabetes, according to a study published early online in the Canadian Medical Association Journal. Bladder cancer is diagnosed... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
New Data Show Higher Bladder Cancer Risk for Smokers (August 29, 2011)New data suggest that the risk of bladder cancer among smokers may be higher than previous estimates. And, though women were thought to have a lower rate of smoking-attributable bladder cancer than men, it now appears that smoking accounts for half of... Continue Reading
More Screening/Prevention Bladder CancerScreening/Prevention Breast Cancer
SERMs Reduce Risk of Breast Cancer (June 12, 2013)
Women who take selective estrogen receptor modulators (SERMs) have a 38 percent reduced risk of breast cancer for up to 10 years after diagnosis and treatment, according to the results of a meta-analysis published in The Lancet. A majority of breast cancers... Continue Reading
Gene Mutations Common In African American Women with Triple-Negative or Early Onset Breast Cancer (June 10, 2013)Among African-American women with breast cancer referred for genetic counseling, one in five had an inherited mutation in at least one of the 18 genes that are linked with breast cancer susceptibility. The frequency of gene mutations was even higher in... Continue Reading
Breast Cancer Deadlier in Women with Cosmetic Implants (June 7, 2013)Breast cancer appears to be more deadly among women with cosmetic breast implants, according to the results of a study published in the British Medical Journal—possibly because it is detected at a more advanced stage. Approximately 200,000 women are... Continue Reading
Delayed Mammography Affects Breast Cancer Mortality in Women Over Age 75 (May 27, 2013)Older women with an extended period of time between their last mammogram and the diagnosis of breast cancer are at an increased risk of dying from the disease, according to the results of a study presented at the American Association for Cancer Research... Continue Reading
False-Positive Mammograms Leave a Long-Term Psychological Impact (May 3, 2013)A false-positive mammogram can cause long-term psychosocial harm, according to the results of a study published in the Annals of Family Medicine—in fact, three years later, women still suffer the psychological after-effects of the scare. A mammogram... Continue Reading
More Screening/Prevention Breast CancerScreening/Prevention Cervical Cancer
HPV Test Appropriate After Indeterminate Pap Test (April 29, 2013)
Women who have an indeterminate Pap smear should undergo human papillomavirus (HPV) testing rather than another Pap smear, according to the results of Cochrane Review. Cancer screening refers to the use of tests to detect cancer in individuals who do... Continue Reading
HPV Vaccination Does Not Lead to Increase in Sex (October 19, 2012)Vaccination against the human papillomavirus (HPV) does not lead to increased sexual activity, according to the results of a study published in the journal Vaccine. HPV is the most common sexually transmitted infection in the United States. There are... Continue Reading
Gardasil is Safe, According to Large Study (October 12, 2012)The HPV vaccine Gardasil® (quadrivalent human papillomavirus [types 6, 11, 16, 18] recombinant vaccine) was found to be safe, according to the results of a large safety study published in the Archives of Pediatrics & Adolescent Medicine. The study... Continue Reading
HPV Testing Can Predict Risk of Cervical Cancer for Up to 18 Years (August 8, 2012)A test for the human papillomavirus (HPV) provides information about a woman’s long-term risk of cervical precancers, according to the results of a study published early online in the Journal of Clinical Oncology. Each year in the United States, there... Continue Reading
HPV Vaccine Reducing Infection among Vaccinated and Unvaccinated (July 16, 2012)The human papillomavirus (HPV) vaccine is reducing infections of virus strains associated with genital warts and cancer, even among those who remain unvaccinated, according to the results of a study published in Pediatrics. HPV is the most common sexually... Continue Reading
More Screening/Prevention Cervical CancerScreening/Prevention Colon Cancer
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)
Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Universal Tumor Testing to Identify Lynch Syndrome (October 30, 2012)Universal tumor MMR testing among patients with colorectal cancer may have a greater sensitivity for identifying Lynch syndrome than other screening strategies, according to the results of a study published in the Journal of the American Medical Association. Lynch... Continue Reading
B Vitamins Do Not Appear to Affect Colorectal Cancer Risk (October 22, 2012)A combination supplement of folic acid, vitamin B6 and vitamin B12 did not statistically significantly increase or decrease the risk of colorectal cancer in older women, according to the results of a study published in the Journal of the National Cancer... Continue Reading
New Colonoscopy Surveillance Guidelines (October 10, 2012)The U.S. Multi-Society Task Force on Colorectal Cancer has released a consensus update regarding colonoscopy surveillance—and the guidelines indicate that average-risk patients who have a clean colonoscopy can wait 10 years between exams. Colorectal... Continue Reading
Colonoscopy Related Factors Associated with Increased Risk of Cancer (August 31, 2012)Incomplete polyp removal and failure to have a follow-up colonoscopy within five years after the detection of the first polyp are more strongly associated with an increased risk of developing colorectal cancer than the characteristics of the polyp, according... Continue Reading
More Screening/Prevention Colon CancerScreening/Prevention Esophageal Cancer
Esophageal Cancer on the Rise (November 12, 2012)
The rate of esophageal cancer is on the rise worldwide, according to the results of a study published in GUT: An International Journal of Gastroenterology and Hepatology, but the onset and magnitude of the increase varies among countries and even states. The... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Barrett’s Esophagus May Carry Lower Risk of Esophageal Cancer Than Previously Reported (July 8, 2011)Barrett’s esophagus—a condition characterized by abnormal cells in the lower part of the esophagus—may carry a lower risk of esophageal cancer than previously reported. These results were published in the Journal of the National Cancer Institute. The... Continue Reading
Cancer Risk May Rise Even with Moderate Drinking (April 15, 2011)People who currently consume alcohol or have done so in the past may have an increased risk of developing cancer, even those who drink moderately. These findings were recently reported in the journal BMJ. Worldwide, an estimated 3.5% of all cancer deaths... Continue Reading
More Screening/Prevention Esophageal CancerScreening/Prevention Gastric Cancer
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
Alcohol Linked with Stomach Cancer (November 7, 2011)According to a large European study, men who average more than four alcoholic beverages per day are more likely than light drinkers to develop stomach cancer. These results were published in the American Journal of Clinical Nutrition. Cancer of the stomach... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Fewer Lung Cancer Deaths Among Women (April 11, 2011)The lung cancer death rate among women appears to be declining for the first time in 40 years, according to an annual report published by multiple institutions. Findings from the report were recently released in the Journal of the National Cancer Institute. A... Continue Reading
More Screening/Prevention Gastric CancerScreening/Prevention Leukemia
Childhood CT Scans Linked to Leukemia and Brain Cancer Later in Life (June 20, 2012)
Children and young adults who undergo multiple computed tomography (CT) scans have an increased risk of leukemia and brain tumors in the decade following their first scan, according to the results of a study published in The Lancet. CT scans are a common... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Greater Cancer Risk Among Taller Women (July 28, 2011)Taller women may have an increased risk of developing certain cancers. Overall, cancer risk increases by 16% for every 4-inch increase in height. These findings were recently reported in Lancet Oncology. Greater insight into height and cancer risk may... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Screening/Prevention LeukemiaScreening/Prevention Liver Cancer
Statins Linked to Lower Risk of Liver Cancer in Hepatitis C (May 8, 2013)
People infected with chronic hepatitis C are less likely to develop liver cancer if they are taking statins (cholesterol-lowering drugs), according to the results of a study published in the Journal of Clinical Oncology.[1] The liver is the largest organ... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Organ Transplant Recipients Have Increased Cancer Risk (November 9, 2011)People who have received a solid organ transplant (such as a kidney or liver) are twice as likely as people in the general population to develop cancer. These results were published in the Journal of the American Medical Association. In 2010, more than... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Cancer Risk May Rise Even with Moderate Drinking (April 15, 2011)People who currently consume alcohol or have done so in the past may have an increased risk of developing cancer, even those who drink moderately. These findings were recently reported in the journal BMJ. Worldwide, an estimated 3.5% of all cancer deaths... Continue Reading
More Screening/Prevention Liver CancerScreening/Prevention Lung Cancer - Non-Small Cell
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)
Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Hormone Replacement Therapy in Newly Menopausal Women May Carry More Benefit Than Risk (October 26, 2012)Hormone replacement therapy for newly menopausal women may not be as risky as once believed, according to the results of a study presented at the 23rd annual meeting of the North American Menopause Society in Orlando, Florida in October 2012.[1] In fact,... Continue Reading
Diesel Exhaust Linked to Lung Cancer (June 26, 2012)Diesel exhaust is associated with an increased risk of lung cancer, according to a press release issued by the World Health Organization (WHO).[1] The announcement came after a group of international experts gathered for a weeklong meeting to review the... Continue Reading
New Lung Cancer Screening Guidelines (May 25, 2012)New lung cancer screening guidelines recommend annual CT scans only for a select group of people—those aged 55 to 74 who are current or former smokers. The guidelines are the result of a systematic review by an expert panel from several medical groups... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Screening/Prevention Lung Cancer - Non-Small CellScreening/Prevention Lung Cancer - Small Cell
Screening Could Reduce Lung Cancer Mortality (April 24, 2013)
Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers could potentially avert approximately 12,000 lung cancer deaths each year in the United States, according to the results of a study... Continue Reading
Diesel Exhaust Linked to Lung Cancer (June 26, 2012)Diesel exhaust is associated with an increased risk of lung cancer, according to a press release issued by the World Health Organization (WHO).[1] The announcement came after a group of international experts gathered for a weeklong meeting to review the... Continue Reading
New Lung Cancer Screening Guidelines (May 25, 2012)New lung cancer screening guidelines recommend annual CT scans only for a select group of people—those aged 55 to 74 who are current or former smokers. The guidelines are the result of a systematic review by an expert panel from several medical groups... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Almost 800,000 Lung Cancer Deaths Prevented (March 22, 2012)Changes in smoking behavior that began in the 1950s prevented close to 800,000 lung cancer deaths between 1975 and 2000. These results were published in the Journal of the National Cancer Institute. Lung cancer remains the leading cause of cancer death... Continue Reading
More Screening/Prevention Lung Cancer - Small CellScreening/Prevention Melanoma
Aspirin Reduces Risk of Melanoma in Women (March 20, 2013)
Women who regularly take aspirin have a reduced risk of developing melanoma, according to the results of a study published in Cancer.[1] What’s more—the longer they take the aspirin, the lower the risk. Of the more than one million new diagnoses of... Continue Reading
Lymphoma Patients and Transplant Recipients at Higher Risk of Melanoma (October 11, 2012)Individuals with lymphoma or those who have undergone organ transplants are far more likely than the average person to develop—and die from—melanoma, according to the results of a review published in Mayo Clinic Proceedings. Melanoma is a potentially... Continue Reading
Number of Cancer Survivors Will Grow to 18 Million by 2022 (June 25, 2012)There will be nearly 18 million cancer survivors in the United States by 2022, according to a report by the American Cancer Society and the National Cancer Institute: Cancer Treatment & Survivorship Facts & Figures[1] and an accompanying journal... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Additional Evidence That Tanning Beds Increase Skin Cancer Risk (November 3, 2011)According to a study of more than 73,000 women, use of tanning beds increases the risk of three common types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. These results were presented at the 10th AACR International Conference... Continue Reading
More Screening/Prevention MelanomaScreening/Prevention Non-Hodgkin's Lymphoma
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Organ Transplant Recipients Have Increased Cancer Risk (November 9, 2011)People who have received a solid organ transplant (such as a kidney or liver) are twice as likely as people in the general population to develop cancer. These results were published in the Journal of the American Medical Association. In 2010, more than... Continue Reading
Greater Cancer Risk Among Taller Women (July 28, 2011)Taller women may have an increased risk of developing certain cancers. Overall, cancer risk increases by 16% for every 4-inch increase in height. These findings were recently reported in Lancet Oncology. Greater insight into height and cancer risk may... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
More Screening/Prevention Non-Hodgkin's LymphomaScreening/Prevention Ovarian Cancer
Ovarian Cancer Rates Declining in Breast Cancer Survivors (February 7, 2013)
The rate of second primary ovarian cancers after first primary breast cancer appears to be on the decline, according to the results of a study published in the Journal of Clinical Oncology. Each year in the United States, roughly 22,000 women are diagnosed... Continue Reading
Diabetes Drug May Help Prevent or Treat Ovarian Cancer (December 3, 2012)Metformin, a widely prescribed insulin-lowering drug for diabetes, has been associated with survival in ovarian cancer and is worthy of further study, as it may be considered for the prevention or treatment of ovarian cancer, according to the results... Continue Reading
Aspirin May Reduce Risk of Serous Ovarian Cancer (October 18, 2012)Women who regularly use aspirin may have a decreased risk of developing serous ovarian cancer, according to the results of a study published in Acta Obstetricia et Gynecologica Scandinavica. Ovarian cancer has the highest mortality rate of all gynecologic... Continue Reading
Healthy Women Need Not Undergo Screening for Ovarian Cancer (April 19, 2012)Healthy women at average risk for ovarian cancer do not need to get screened for the disease, according to the U.S. Preventive Services Task Force (USPSTF). After a recent review of the data, the government panel has renewed its 2004 recommendation against... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Screening/Prevention Ovarian CancerScreening/Prevention Pancreatic Cancer
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)
A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
Test Holds Promise for Early Detection of Pancreatic Cancer (January 24, 2012)A test that detects a particular protein in the blood (PAM4) correctly identified roughly two-thirds of patients with early-stage pancreatic cancer. These results were presented at the 2012 Gastrointestinal Cancers Symposium. Pancreatic cancer is one... Continue Reading
Processed Meat Linked with Increased Risk of Pancreatic Cancer (January 18, 2012)Eating processed meat such as sausage or bacon appears to increase the risk of pancreatic cancer. These results were published in the British Journal of Cancer. Pancreatic cancer is one of the deadliest forms of cancer. Each year, close to 44,000 people... Continue Reading
Stay on Top of Your Family History of Cancer (July 15, 2011)People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s important to update this information periodically... Continue Reading
More Screening/Prevention Pancreatic CancerScreening/Prevention Prostate Cancer
Prostate Cancer Screening Can Take a Toll on Quality of Life (December 19, 2012)
Screening for prostate cancer carries some risks and can affect quality of life. Considering these risks is important when making the decision about whether to be screened. The results of a study that assessed both the potential benefits of screening... Continue Reading
Aspirin and Cancer Risk and Mortality (September 17, 2012)Aspirin and cancer risk is in the news again—and the link is still unclear. Two studies published early online in the Journal of Clinical Oncology evaluated the relationship between aspirin and cancer risk—one indicated that aspirin does not appear... Continue Reading
New Screening Method May Help Diagnose Undetectable Prostate Cancer (August 16, 2012)Men with persistently increased or fluctuating prostate specific antigen (PSA) levels and a negative prostate biopsy may benefit from a new prostate cancer screening method that uses the combination of a novel drug therapy plus changes in PSA levels over... Continue Reading
PSA Testing May Be Appropriate for Some Men (July 25, 2012)The American Society of Clinical Oncology (ASCO) has released a Provisional Clinical Opinion (PCO) suggesting that that men with a longer life expectancy—those with at least 10 more years to live—discuss with their physician the potential risks and... Continue Reading
Number of Cancer Survivors Will Grow to 18 Million by 2022 (June 25, 2012)There will be nearly 18 million cancer survivors in the United States by 2022, according to a report by the American Cancer Society and the National Cancer Institute: Cancer Treatment & Survivorship Facts & Figures[1] and an accompanying journal... Continue Reading
More Screening/Prevention Prostate CancerScreening/Prevention Rectal Cancer
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)
Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
New Colonoscopy Surveillance Guidelines (October 10, 2012)The U.S. Multi-Society Task Force on Colorectal Cancer has released a consensus update regarding colonoscopy surveillance—and the guidelines indicate that average-risk patients who have a clean colonoscopy can wait 10 years between exams. Colorectal... Continue Reading
Sigmoidoscopy Screening Reduces Colorectal Cancer Incidence and Mortality (May 29, 2012)Sigmoidoscopy, a less-invasive screening procedure that examines the lower portion of the bowel, can reduce the risk of developing colorectal cancer or dying from it, according to the results of a study published in the New England Journal of Medicine. Colorectal... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Evidence That Colonoscopy Reduces Deaths from Colorectal Cancer (February 24, 2012)Removal of polyps during colonoscopy substantially reduces the risk of death from colorectal cancer, providing further support for use of colonoscopy as a colorectal cancer screening test. These results were published in the New England Journal of Medicine. Colorectal... Continue Reading
More Screening/Prevention Rectal CancerScreening/Prevention Uterine Cancer
Number of Cancer Survivors Will Grow to 18 Million by 2022 (June 25, 2012)
There will be nearly 18 million cancer survivors in the United States by 2022, according to a report by the American Cancer Society and the National Cancer Institute: Cancer Treatment & Survivorship Facts & Figures[1] and an accompanying journal... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Lynch Syndrome Also Linked with Breast and Pancreatic Cancer (February 17, 2012)A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in... Continue Reading
Myotonic Muscular Dystrophy Linked with Increased Cancer Risk (December 19, 2011)People with myotonic muscular dystrophy may be more likely than people in the general population to develop certain types of cancer. These results were published in the Journal of the American Medical Association. Myotonic muscular dystrophy (MMD) is... Continue Reading
Coffee May Cut Uterine Cancer Risk (November 30, 2011)Women who consume four or more cups a coffee per day may have a lower risk of endometrial cancer (cancer of the lining of the uterus) than women who drink very little or no coffee. These results were published in Cancer Epidemiology, Biomarkers, &... Continue Reading
More Screening/Prevention Uterine CancerSkin Cancer
Some Squamous Cell Skin Cancers Are Deadly (June 19, 2013)
Cutaneous squamous cell carcinoma is usually easily treated with surgery; however, a subsection of patients with specific disease risk factors are more likely to develop metastases and die from the disease, according to the results of a study published... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Coffee Might Reduce the Risk of Basal Cell Carcinoma (July 11, 2012)Good news for coffee lovers—drinking caffeinated coffee could lower the risk of developing basal cell carcinoma, according to the results of a study published in Cancer Research. The Harvard study found that increased caffeine intake was associated... Continue Reading
Erivedge Effective in Basal-Cell Carcinoma (June 21, 2012)The targeted agent Erivedge™ (vismodegib) is associated with tumor responses in patients with locally advanced or metastatic basal-cell carcinoma and may even reduce the rate of new basal-cell carcinomas, according to the results of two studies published... Continue Reading
More Skin CancerSkin Cancer Overview
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More Skin Cancer OverviewStage I Cervical Cancer
Sentinel Node Biopsy Is a Minimally-invasive, Effective Method for Determining Spread of Cervical Cancer (June 9, 2009)
Sentinel Node Biopsy Is a Minimally-invasive, Effective Method for Determining Spread of Cervical Cancer The majority of women with cervical cancer can safely undergo sentinel node biopsy instead of full pelvic lymph node dissection to determine the spread... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer (March 8, 2009)Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer Robotically-assisted hysterectomy (RAH) in patients with early-stage cervical cancer is at least as effective as traditional open radical hysterectomy (ORH) and produces fewer complications,... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Stage I Cervical CancerStage I Node Negative Breast Cancer
SERMs Reduce Risk of Breast Cancer (June 12, 2013)
Women who take selective estrogen receptor modulators (SERMs) have a 38 percent reduced risk of breast cancer for up to 10 years after diagnosis and treatment, according to the results of a meta-analysis published in The Lancet. A majority of breast cancers... Continue Reading
Breast-Conserving Therapy Comparable to Mastectomy for Women with Early-Stage Triple-Negative Breast Cancer (May 23, 2013)In a study of more than 600 women with early-stage triple-negative breast cancer treated at a single institution, treatment with breast-conserving therapy was as effective as total mastectomy. These results were published in Annals of Surgery Oncology. Breast-conserving... Continue Reading
Lymphoseek Approved for Detecting Lymph Nodes in Breast Cancer and Melanoma (April 10, 2013)The U.S. Food and Drug Administration (FDA) has approved Lymphoseek® (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing... Continue Reading
Radiation for Breast Cancer Increases Risk of Heart Disease and Heart Attack (March 27, 2013)Exposure to ionizing radiation during radiation therapy for breast cancer may increase the risk of heart attack or heart disease later in life, according to the results of a study published in the New England Journal of Medicine. Many women with breast... Continue Reading
Prognosis of Triple-Negative Breast Cancer Varies By Age (March 19, 2013)The prognosis of triple-negative breast cancer (TNBC) tends to be better among older women than among younger women, even though older women are less likely to receive aggressive treatment. These results were published in Breast Cancer Research and Treatment. Previous... Continue Reading
More Stage I Node Negative Breast CancerStage I Ovarian Cancer
Ovarian Cancer Rates Declining in Breast Cancer Survivors (February 7, 2013)
The rate of second primary ovarian cancers after first primary breast cancer appears to be on the decline, according to the results of a study published in the Journal of Clinical Oncology. Each year in the United States, roughly 22,000 women are diagnosed... Continue Reading
Diabetes Drug May Help Prevent or Treat Ovarian Cancer (December 3, 2012)Metformin, a widely prescribed insulin-lowering drug for diabetes, has been associated with survival in ovarian cancer and is worthy of further study, as it may be considered for the prevention or treatment of ovarian cancer, according to the results... Continue Reading
Treatment at High-Volume Hospitals Leads to Lower Mortality Rates for Ovarian Patients (November 20, 2012)Ovarian cancer patients who undergo surgery at high-volume hospitals have better outcomes than those who are treated at low-volume hospitals, according to the results of a study published in the Journal of Clinical Oncology. This is the result not of... Continue Reading
Gene Helps Predict Response to Chemotherapy in Ovarian Cancer (September 28, 2012)Measuring the activity of a gene called FGF1 could help predict which women with ovarian cancer will benefit from platinum-based chemotherapy, according to the results of a study published in the British Journal of Cancer. Each year in the United States,... Continue Reading
BRCA Genes May Influence Ovarian Cancer Outcomes (October 24, 2011)Among women with ovarian cancer, those who have a BRCA2 gene mutation may have a better response to chemotherapy and longer survival than those who do not have a BRCA gene mutation. These results were published in the Journal of the American Medical Association. Inherited... Continue Reading
More Stage I Ovarian CancerStage I-II Testicular Cancer
Marijuana May Increase Risk of Testicular Cancer (September 21, 2012)
Recreational marijuana use may increase the risk of developing subtypes of testicular cancer that have a worse prognosis, according to the results of a study published early online in the journal Cancer. Testicular cancer is the most common cancer diagnosed... Continue Reading
Low-Dose CT Scans Effective for Surveillance of Early Testicular Cancer (June 15, 2011)Low-dose computed tomography (CT) scans provide a reliable method for surveillance and reduce radiation exposure by 40-60% among patients with Stage I testicular cancer. These results were recently presented at the 2011 annual meeting of the American... Continue Reading
New Genes Linked to Testicular Cancer (June 28, 2010)Scientists have discovered three new genes associated with testicular cancer, according to the results of a study published in Nature Genetics.[1] Testicular cancer is the most common type of cancer in men ages 15 to 45. The incidence of testicular cancer... Continue Reading
Men with Infertility May Have Increased Risk of Testicular Cancer (March 8, 2009)Men with Infertility May Have Increased Risk of Testicular Cancer Men with infertility are three times more likely to develop testicular cancer compared with fertile men, according to the results of a study published in the Archives of Internal Medicine.[1] The... Continue Reading
Single Dose of Carboplatin as Effective as Radiation Therapy for Testicular Cancer (March 8, 2009)Single Dose of Carboplatin as Effective as Radiation Therapy for Testicular Cancer Among men with Stage I seminoma (a type of testicular cancer), post-surgery treatment with a single dose of the chemotherapy drug carboplatin is as effective as two to... Continue Reading
More Stage I-II Testicular CancerStage I/Smoldering Myeloma Multiple Myeloma
Continuous Revlimid May Improve Outcomes in Newly Diagnosed Multiple Myeloma (December 15, 2010)
Among older patients with newly diagnosed multiple myeloma, treatment with Revlimid® (lenalidomide) in combination with melphalan and prednisone, followed by Revlimid maintenance therapy (MPR-R) may result in better progression-free survival than two... Continue Reading
Revlimid Maintenance Slows Myeloma Progression After Stem Cell Transplant (December 14, 2010)Maintenance therapy with Revlimid® (lenalidomide) reduced the risk of myeloma progression or death by 60% among patients who had undergone an autologous stem cell transplant. These updated results from a Phase III clinical trial were presented at the... Continue Reading
Improved Survival with Zometa in Multiple Myeloma (December 14, 2010)It appears that treatment of patients with newly diagnosed multiple myeloma with Zometa® (zoledronic acid) may improve overall survival and progression-free survival. These findings were recently reported in The Lancet. Multiple myeloma is a cancer of... Continue Reading
Combination of Velcade and Revlimid Promising Against Newly Diagnosed Multiple Myeloma (October 29, 2010)Among patients with symptomatic newly diagnosed multiple myeloma, treatment with a combination of Revlimid® (lenalidomide), Velcade® (bortezomib), and dexamethasone produced a partial response or better in 100% of patients. The results of this Phase... Continue Reading
Denosumab More Effective Than Zometa at Delaying Bone Complications (October 15, 2010)Among patients with multiple myeloma or bone metastases from breast cancer, prostate cancer, or other solid tumors, denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. Results from... Continue Reading
More Stage I/Smoldering Myeloma Multiple MyelomaStage II-IV Ovarian Cancer
Maintenance Therapy with Votrient Provides Benefit in Advanced Ovarian Cancer (June 13, 2013)
In a Phase III clinical trial, treatment with Votrient® (pazopanib) after initial chemotherapy improved outcomes among women with advanced ovarian cancer. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology... Continue Reading
Delaying Chemotherapy Increases Mortality in Ovarian Cancer (April 12, 2013)Women with advanced ovarian cancer have significantly worse survival when they wait more than 25 days after surgery to start chemotherapy, according to the results of a study presented at the 2013 Society of Gynecologic Oncology Annual Meeting on Women’s... Continue Reading
Ovarian Cancer Rates Declining in Breast Cancer Survivors (February 7, 2013)The rate of second primary ovarian cancers after first primary breast cancer appears to be on the decline, according to the results of a study published in the Journal of Clinical Oncology. Each year in the United States, roughly 22,000 women are diagnosed... Continue Reading
Diabetes Drug May Help Prevent or Treat Ovarian Cancer (December 3, 2012)Metformin, a widely prescribed insulin-lowering drug for diabetes, has been associated with survival in ovarian cancer and is worthy of further study, as it may be considered for the prevention or treatment of ovarian cancer, according to the results... Continue Reading
Treatment at High-Volume Hospitals Leads to Lower Mortality Rates for Ovarian Patients (November 20, 2012)Ovarian cancer patients who undergo surgery at high-volume hospitals have better outcomes than those who are treated at low-volume hospitals, according to the results of a study published in the Journal of Clinical Oncology. This is the result not of... Continue Reading
More Stage II-IV Ovarian CancerStage III Bladder Cancer
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)
Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
Study Explores New Approach to Boosting the Immune System after Cancer Treatment (August 24, 2011)Researchers are seeking participants for a Phase II clinical trial that will explore whether an investigational treatment can help the immune system recover after cancer treatment. Cancer treatments such as chemotherapy and radiation therapy often deplete... Continue Reading
More Stage III Bladder CancerStage III Melanoma
Intermittent Zelboraf Treatment in Patients with Melanoma May Prevent Resistance to the Drug (May 22, 2013)
Tumors resistant to Zelboraf® (vemurafenib) in patients with melanoma showed reduced growth after treatment was stopped. What’s more—animal models have shown that drug resistance was prevented by intermittent treatment. These results were presented... Continue Reading
Adjuvant Radiotherapy for the Management of High-Risk Malignant Melanoma (September 24, 2012)Adjuvant radiotherapy significantly improved regional lymphatic control for high-risk patients after therapeutic lymphadenectomy for metastatic melanoma, according to the results of a study published in the Lancet Oncology. Of the more than one million... Continue Reading
Melanoma Drug Accelerates Secondary Skin Cancers In Some Patients (January 23, 2012)Zelboraf® (vemurafenib) improves outcomes among patients with advanced melanoma that harbors a BRAF gene mutation, but also accelerates the development of squamous cell carcinoma in some patients. A study that explores the reasons for these secondary... Continue Reading
Zelboraf (Vemurafenib) Approved for Melanoma (August 22, 2011)The targeted therapy Zelboraf™ (vemurafenib) has been approved by the US Food and Drug Administration (FDA) for the treatment of melanomas that carry a common mutation in the BRAF gene. Of the more than one million new diagnoses of skin cancer each... Continue Reading
Sentinel Node Biopsy Safe and Effective for Melanomas on Head and Neck (August 10, 2011)Although the head and neck region is complex and delicate, sentinel lymph node biopsy for melanomas of the head or neck appears to be safe and effective. These results were published in Cancer. Skin cancer is the most commonly diagnosed cancer in the... Continue Reading
More Stage III MelanomaStage III Testicular Cancer
Marijuana May Increase Risk of Testicular Cancer (September 21, 2012)
Recreational marijuana use may increase the risk of developing subtypes of testicular cancer that have a worse prognosis, according to the results of a study published early online in the journal Cancer. Testicular cancer is the most common cancer diagnosed... Continue Reading
New Genes Linked to Testicular Cancer (June 28, 2010)Scientists have discovered three new genes associated with testicular cancer, according to the results of a study published in Nature Genetics.[1] Testicular cancer is the most common type of cancer in men ages 15 to 45. The incidence of testicular cancer... Continue Reading
More Stage III Testicular CancerStage IV (D)/Relapsed Colon Cancer
Erbitux Plus Chemo Boosts Survival in Patients with Colorectal Cancer and Liver Metastases (May 29, 2013)
Adding Erbitux® (cetuximab) to standard chemotherapy might allow some patients with colorectal cancer and inoperable liver metastases to undergo successful surgical resection of the liver metastasis, according to the results of a study published in the Journal... Continue Reading
Combo Treatment Effective in Elderly Patients with Metastatic Colorectal Cancer (March 6, 2013)Combination therapy with Avastin® (bevacizumab) and Xeloda® (capecitabine) may be an optimal first-line treatment for treatment-naïve older patients with metastatic colorectal cancer, according to the results of a study presented at the 2013 Gastrointestinal... Continue Reading
Neulasta Significantly Reduces Febrile Neutropenia Among Colorectal Cancer Patients Receiving Chemotherapy Plus Avasatin (February 25, 2013)Neulasta® (pegfilgrastim) significantly reduced the incidence of grade 3/4 febrile neutropenia among patients with locally advanced or metastatic colorectal cancer who received chemotherapy with FOLFOX or FOLFIRI followed by Avastin® (bevacizumab),... Continue Reading
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Zaltrap Improves Survival in Metastatic Colorectal Cancer (October 16, 2012)The addition of Zaltrap® (ziv-aflibercept) to the FOLFIRI chemotherapy regimen improved overall survival in patients with metastatic colorectal cancer who were previously treated with Eloxatin® (oxaliplatin), according to the results of a phase III... Continue Reading
More Stage IV (D)/Relapsed Colon CancerStage IV Anal Cancer
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)
Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
No Benefit with Addition of Platinol® to Treatment for Anal Cancer (May 1, 2008)No Benefit with Addition of Platinol® to Treatment for Anal Cancer Addition of the drug Platinol® (cisplatin) to 5-FU (5-flourouracil), mitomycin, and radiation may not improve outcomes for patients with anal cancer. These findings were recently published... Continue Reading
More Stage IV Anal CancerStage IV Liver Cancer
Nexavar Superior to Sutent in Liver Cancer (June 23, 2011)
Nexavar® (sorafenib) provides superior overall survival to Sutent® (sunitinib) in the treatment of hepatocellular (liver) cancer. These results were presented at the 2011 annual American Society of Clinical Oncology (ASCO) meeting. Hepatocellular carcinoma... Continue Reading
Cabozantinib Shows Promise against Bone Metastases (May 31, 2011)The investigational drug cabozantinib is showing promise against several types of advanced cancer, and may also reduce or eliminate bone metastases (cancer that has spread to the bone) in some patients. These results will be presented at the 2011 annual... Continue Reading
FDA Grants Orphan Drug Status to Investigational Liver Cancer Drug (May 2, 2011)PV-10—an investigational liver cancer drug—has been designated an orphan drug by the US Food and Drug Administration (FDA). The orphan drug designation is intended to encourage the development of drugs for rare diseases by providing incentives for... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Combination Chemotherapy Improves Survival with Biliary Tract Cancer (May 17, 2010)According to the results of a Phase III clinical trial, treatment of locally advanced or metastatic biliary tract cancer with a combination of Gemzar® (gemcitabine) and cisplatin results in better survival and a lower risk of cancer progression than... Continue Reading
More Stage IV Liver CancerStage IV Melanoma
Immunotherapy Combination Promising for Metastatic Melanoma (June 14, 2013)
For people with metastatic melanoma, treatment with a combination of Yervoy® (ipilimumab) and Leukine® (sargramostim; GM-CSF) may result in better overall survival than treatment with Yervoy alone. These results, from a Phase II clinical trial, were... Continue Reading
Intermittent Zelboraf Treatment in Patients with Melanoma May Prevent Resistance to the Drug (May 22, 2013)Tumors resistant to Zelboraf® (vemurafenib) in patients with melanoma showed reduced growth after treatment was stopped. What’s more—animal models have shown that drug resistance was prevented by intermittent treatment. These results were presented... Continue Reading
Combined Targeted Therapy Safe and Effective in Metastatic Melanoma (October 24, 2012)Treatment with a combination of two targeted agents—dabrafenib, which targets BRAF, and trametinib, which targets MEK—in patients with metastatic melanoma and BRAF V600 mutations was safe and improved progression-free survival, according to the results... Continue Reading
PD-1 Targeted Immune Therapy Shows Promising Activity (June 11, 2012)The investigational drug BMS-936558 caused tumor shrinkage in nearly 25 percent of patients with advanced melanoma, kidney cancer and non-small cell lung cancer (NSCLC), according to the results of a phase I study presented at the 2012 annual meeting... Continue Reading
Zelboraf Improves Melanoma Survival (March 16, 2012)Among patients with previously treated metastatic melanoma that carries a certain gene mutation, the targeted drug Zelboraf® (vemurafenib) resulted in a median overall survival of 16 months. This is a substantial improvement over what has been seen in... Continue Reading
More Stage IV MelanomaStage IV Pancreatic Cancer
Abraxane Improves Survival in Pancreatic Cancer (February 13, 2013)
Abraxane® (nab-paclitaxel) prolonged life in patients with metastatic pancreatic cancer by an average of two months longer than chemotherapy and significantly increased the percentage of patients who survived for up to two years, according to the results... Continue Reading
Sutent Approved for Pancreatic Neuroendocrine Tumors (PNET) (June 2, 2011)The US Food and Drug Administration has approved the targeted drug Sutent® (sunitinib) for the treatment pancreatic neuroendocrine tumors (PNET). Pancreatic neuroendocrine tumors are an uncommon type of cancer that develops in the hormone-producing cells... Continue Reading
Novel Chemotherapy Regimen Outperforms Gemzar for Pancreatic Cancer (May 18, 2011)For people with metastatic pancreatic cancer, the chemotherapy combination known as FOLFIRINOX results in better overall survival than standard treatment with Gemzar® (gemcitabine), but also increases side effects. These results were published in the... Continue Reading
New Approach to Immune Therapy Shows Promise against Pancreatic Cancer (April 1, 2011)An investigational type of immune therapy that attacks the tissue around a tumor has shown promise in a small study of patients with advanced pancreatic cancer. These results were published in the journal Science. Immune therapies stimulate the body’s... Continue Reading
Addition of Axitinib Fails to Improve Pancreatic Cancer Outcomes (February 23, 2011)Among patients with advanced pancreatic cancer, treatment with a combination of Gemzar® (gemcitabine) and the investigational drug axitinib did not result in better outcomes than treatment with Gemzar alone. The results of this Phase III clinical trial... Continue Reading
More Stage IV Pancreatic CancerStage IV Rectal Cancer
Erbitux Plus Chemo Boosts Survival in Patients with Colorectal Cancer and Liver Metastases (May 29, 2013)
Adding Erbitux® (cetuximab) to standard chemotherapy might allow some patients with colorectal cancer and inoperable liver metastases to undergo successful surgical resection of the liver metastasis, according to the results of a study published in the Journal... Continue Reading
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Zaltrap Approved for Metastatic Colorectal Cancer (August 15, 2012)The U.S. Food and Drug Administration (FDA) has approved Zaltrap® (ziv-aflibercept) for use in combination with the FOLFIRI chemotherapy regimen (folinic acid, fluorouracil, and ironotecan) to treat adults with metastatic colorectal cancer. Colorectal... Continue Reading
Regorafenib Shows Promise Against Metastatic Colorectal Cancer (January 19, 2012)The investigational drug regorafenib improves survival and delays cancer progression among patients with metastatic colorectal cancer that has worsened in spite of other treatments. These results will be presented at the 2012 Gastrointestinal Cancers... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
More Stage IV Rectal CancerStage IV Uterine Cancer
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)
Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Risk Factors Identified for Uterine Sarcoma Survival (March 8, 2009)Risk Factors Identified for Uterine Sarcoma Survival Survival for patients diagnosed with uterine leiomyosarcomas may be influenced by several factors. These findings were recently published in the journal Cancer. The uterus is located in the abdomen... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Stage IV Uterine CancerStage IV/Metastatic Bladder Cancer
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)
Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
Adding Chemotherapy to Radiation Reduces Bladder Cancer Recurrence (April 30, 2012)Chemotherapy plus radiation reduces the risk of recurrence in muscle-invasive bladder cancer patients by nearly 50% compared to radiation alone, according to the results of a study published in the New England Journal of Medicine.[1] Bladder cancer is... Continue Reading
Liposomal Cisplatin Safe for Patients with Renal Insufficiency (June 14, 2011)Liposomal cisplatin (Nanoplatin®), a chemotherapy drug still in clinical trials, does not cause damage to the kidneys and appears to provide at least equal anti-cancer effects as cisplatin (Platinol®) among cancer patients with renal insufficiency.... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
New Bladder-preserving Therapy Promising in Bladder Cancer (November 9, 2010)A new bladder-preserving approach to treatment of locally invasive bladder cancer appears promising, both for patients for whom radical cystectomy is indicated and for those previously ineligible for curative treatment. These findings were recently published... Continue Reading
More Stage IV/Metastatic Bladder CancerStage IV/Recurrent Esophageal Cancer
Second-Line Docetaxel Improves Survival in Esophageal and Gastric Cancer (April 3, 2013)
Second-line treatment with docetaxel improves overall survival of patients with advanced esophageal and gastric cancer, according to the results of a study presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco. The esophagus is a muscular... Continue Reading
Surgery Improves Survival in Esophageal Cancer (February 21, 2013)Surgery after chemoradiotherapy—which is the standard of care in advanced esophageal cancer—increased overall and disease-free survival compared with chemoradiotherapy alone, according to the results of a study presented at the 2013 Gastrointestinal... Continue Reading
Iressa Improves Progression-Free Survival in Metastatic Esophageal Cancer (October 5, 2012)Treatment with Iressa® (gefitinib) slowed disease progression and improved quality of life in patients with metastatic esophageal cancer, according to the results of a phase III trial presented at the ESMO 2012 Congress of the European Society for Medical... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Some Patients with Advanced Cancer Continue Screening (October 22, 2010)A significant proportion of patients with advanced cancers continue to undergo cancer screening, even though screening is unlikely to benefit these patients. These findings were recently reported in the Journal of the American Medical Association. Cancer... Continue Reading
More Stage IV/Recurrent Esophageal CancerStages 0-I Bladder Cancer
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)
Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
More Stages 0-I Bladder CancerStages I-II Anal Cancer
Intensity-Modulated Radiation Therapy Reduces Side Effects for Patients with Anal Cancer (January 31, 2011)
Treatment of anal cancer with chemotherapy and intensity-modulated radiation therapy (IMRT) may be as effective as treatment with conventional radiation and chemotherapy but with fewer side effects. These findings were presented at the eighth annual Gastrointestinal... Continue Reading
No Benefit with Addition of Platinol® to Treatment for Anal Cancer (May 1, 2008)No Benefit with Addition of Platinol® to Treatment for Anal Cancer Addition of the drug Platinol® (cisplatin) to 5-FU (5-flourouracil), mitomycin, and radiation may not improve outcomes for patients with anal cancer. These findings were recently published... Continue Reading
More Stages I-II Anal CancerStages I-II Gastric Cancer
Adjuvant Radiochemotherapy Demonstrates Benefit in Gastric Cancer (September 25, 2012)
Adjuvant radiochemotherapy provides strong and persistent benefit in patients who have undergone curative gastric resection, according to the long-term results of a study published in the Journal of Clinical Oncology.[1] Gastric cancer refers to cancer... Continue Reading
XELOX May Improve Survival in Gastric Cancer (June 24, 2011)The chemotherapy regimen referred to as XELOX may improve overall survival compared with observation alone in stages II and III gastric (stomach) cancer; however, data are still immature and longer follow-up is necessary. These results were presented... Continue Reading
Genetic Variant Associated with Poor Outcome for Gastric Cancer (May 24, 2010)Patients with gastric cancer who have a certain type of inherited variation in the CD44 gene experience a significantly shorter time to disease recurrence (2.1 years) compared with patients without the genetic variation (seven years), according to the... Continue Reading
Adjuvant Chemotherapy Clinical Trial Data from Last 30 Years Evaluated to Determine Benefit in Gastric Cancer (May 14, 2010)A moderate but statistically significant survival benefit was reported with the addition of chemotherapy to surgery in patients with resectable gastric cancer (gastric cancer that can be surgically removed). These findings were recently published in... Continue Reading
In Gastric Cancer Antibiotics Following Surgery Reduce Risk of Second Gastric Cancer (March 8, 2009)In Gastric Cancer Antibiotics Following Surgery Reduce Risk of Second Gastric Cancer Among patients diagnosed with gastric (stomach) cancer, a combination of antibiotics against the bacterium Helicobacter pylori (H. pylori) significantly reduces the risk... Continue Reading
More Stages I-II Gastric CancerStages I-II Melanoma
Lymphoseek Approved for Detecting Lymph Nodes in Breast Cancer and Melanoma (April 10, 2013)
The U.S. Food and Drug Administration (FDA) has approved Lymphoseek® (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing... Continue Reading
Women More Likely to Survive Melanoma Than Men (May 16, 2012)Women are 30 percent more likely to survive melanoma than men, according to the results of a study published in the Journal of Clinical Oncology.[1] Melanoma is a deadly type of skin cancer that arises from melanocytes, which are cells located in the... Continue Reading
Sentinel Node Biopsy Safe and Effective for Melanomas on Head and Neck (August 10, 2011)Although the head and neck region is complex and delicate, sentinel lymph node biopsy for melanomas of the head or neck appears to be safe and effective. These results were published in Cancer. Skin cancer is the most commonly diagnosed cancer in the... Continue Reading
Wealthy Women at Higher Risk of Melanoma (April 6, 2011)It appears that wealthier White women may be at a higher risk of melanoma than less affluent women. These findings were recently published in the Archives of Dermatology. Melanoma is the most deadly type of skin cancer. Each year in the United States,... Continue Reading
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
More Stages I-II MelanomaStages I-III Esophageal Cancer
Surgery Improves Survival in Esophageal Cancer (February 21, 2013)
Surgery after chemoradiotherapy—which is the standard of care in advanced esophageal cancer—increased overall and disease-free survival compared with chemoradiotherapy alone, according to the results of a study presented at the 2013 Gastrointestinal... Continue Reading
Surgeon Volume Influences Outcomes in Esophageal Cancer (February 6, 2013)Patients who undergo surgery for esophageal cancer have a much higher chance of long-term survival if the surgeon has performed the operation many times before, according to the results of a study published in the Journal of Clinical Oncology. The esophagus... Continue Reading
Preoperative Chemoradiotherapy Improves Survival in Esophageal Cancer (September 10, 2012)Preoperative chemoradiotherapy doubled median overall survival among patients with esophageal or esophagogastric junction cancer compared to surgery alone, according to the results of a phase 3 study published in the New England Journal of Medicine. The... Continue Reading
Minimally Invasive Surgery a Viable Option for Esophageal Cancer (June 26, 2012)Minimally invasive surgery may provide short-term benefits in resectable esophageal cancer, reducing the risk of pulmonary infection and improving quality of life, according to the results of a study published in The Lancet. The esophagus is a muscular... Continue Reading
ERCC1 Levels Strongly Associated with Survival in Esophageal Cancer (June 13, 2011)Levels of expression of a specific gene (ERCC1 gene) are strongly associated with survival outcomes among patients with operable esophageal cancer undergoing platinum-based chemotherapy. Results such as these may help guide personalized treatment options... Continue Reading
More Stages I-III Esophageal CancerStages I-III Liver Cancer
Antiviral Therapy May Reduce the Risk of Tumor Recurrence in HBV-Related Liver Cancer (November 26, 2012)
Patients with hepatitis B-related liver cancer who receive antiviral drugs after curative surgery have a lower risk of recurrence compared to those who do not receive antiviral therapy, according to the results of a study published in the Journal of the... Continue Reading
Nexavar Superior to Sutent in Liver Cancer (June 23, 2011)Nexavar® (sorafenib) provides superior overall survival to Sutent® (sunitinib) in the treatment of hepatocellular (liver) cancer. These results were presented at the 2011 annual American Society of Clinical Oncology (ASCO) meeting. Hepatocellular carcinoma... Continue Reading
Combination Chemotherapy Improves Survival with Biliary Tract Cancer (May 17, 2010)According to the results of a Phase III clinical trial, treatment of locally advanced or metastatic biliary tract cancer with a combination of Gemzar® (gemcitabine) and cisplatin results in better survival and a lower risk of cancer progression than... Continue Reading
Sutent® Not Effective for Advanced Liver Cancer (July 10, 2009)In a Phase II clinical trial, patients with inoperable, advanced hepatocellular (liver) cancer did not benefit from treatment with the targeted therapy Sutent® (sunitinib). The results of this study were published in Lancet Oncology. Hepatocellular carcinoma... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Liver Cancer (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Liver Cancer Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison studies... Continue Reading
More Stages I-III Liver CancerStages I-III Pancreatic Cancer
Sutent Approved for Pancreatic Neuroendocrine Tumors (PNET) (June 2, 2011)
The US Food and Drug Administration has approved the targeted drug Sutent® (sunitinib) for the treatment pancreatic neuroendocrine tumors (PNET). Pancreatic neuroendocrine tumors are an uncommon type of cancer that develops in the hormone-producing cells... Continue Reading
New Approach to Immune Therapy Shows Promise against Pancreatic Cancer (April 1, 2011)An investigational type of immune therapy that attacks the tissue around a tumor has shown promise in a small study of patients with advanced pancreatic cancer. These results were published in the journal Science. Immune therapies stimulate the body’s... Continue Reading
Addition of Axitinib Fails to Improve Pancreatic Cancer Outcomes (February 23, 2011)Among patients with advanced pancreatic cancer, treatment with a combination of Gemzar® (gemcitabine) and the investigational drug axitinib did not result in better outcomes than treatment with Gemzar alone. The results of this Phase III clinical trial... Continue Reading
Gemzar Versus 5-FU for Adjuvant Treatment of Pancreatic Cancer (September 21, 2010)A large randomized study demonstrated no significant improvement in survival with Gemzar® (gemcitabine) versus 5-fluorouracil (5-FU) for the adjuvant (post-surgery) treatment of pancreatic cancer. These findings were recently published in the Journal... Continue Reading
November Is National Pancreatic Cancer Awareness Month (November 5, 2009)As the month of November brings pancreatic cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated pancreatic... Continue Reading
More Stages I-III Pancreatic CancerStages I-III Rectal Cancer
Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers (November 6, 2012)
Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death... Continue Reading
Adjuvant Therapy May Offer Survival Benefit in Older Patients with Colorectal Cancer (September 11, 2012)Adjuvant chemotherapy appears to offer a survival benefit to patients aged 75 years or older who have surgically resected colorectal cancer, according to the results of a study published in the Journal of Clinical Oncology. Colorectal cancer is the second... Continue Reading
Rectal Cancer Patients May Benefit from Higher Dose of Preoperative Radiation (October 12, 2011)Among rectal cancer patients treated with chemotherapy and radiation therapy prior to surgery, providing a higher dose of radiation therapy (50 Gy rather than 45 Gy) may reduce the risk of cancer recurrence. These results were presented at the 53rd Annual... Continue Reading
African Americans Most Willing to Exhaust Resources for Life-Extending Care (May 5, 2011)African Americans who are diagnosed with lung or colorectal cancer may be more willing than Whites to expend all personal financial resources in order to extend their lives. Other minority groups also appear more likely than Whites to use personal resources.... Continue Reading
Pathological Complete Response Predicts Better Outcomes in Locally Advanced Rectal Cancer Patients (August 25, 2010)Among patients with locally advanced rectal cancer, a complete disappearance of detectable cancer (pathological complete response) after preoperative chemoradiation therapy is linked with better long-term outcomes. These findings were recently published... Continue Reading
More Stages I-III Rectal CancerStages I-III Uterine Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Laparoscopic Hysterectomy for Endometrial Cancer Associated with Better Quality of Life (August 3, 2010)Laparoscopic hysterectomy for endometrial cancer that is confined to the uterus is associated with less pain, shorter hospital stays, faster recovery, and better quality of life when compared with total abdominal hysterectomy, according to the results... Continue Reading
Vaginal Brachytherapy Effective for Endometrial Cancer (March 17, 2010)Among women who have undergone surgery for high-intermediate risk endometrial cancer, vaginal brachytherapy is as effective as pelvic external beam radiotherapy in the prevention of vaginal recurrence and produces fewer side effects. These results... Continue Reading
Adjuvant Radiation Therapy May Improve Survival in Stage III Uterine Cancer (October 22, 2009)Among women with node-positive Stage III uterine cancer, use of adjuvant (post-surgery) radiation therapy appears to improve survival. These results were published in Gynecologic Oncology. Stage III uterine cancer extends outside the uterus but remains... Continue Reading
Removal of Ovaries May Not Be Necessary in Young Women with Endometrial Cancer (March 8, 2009)Removal of Ovaries May Not Be Necessary in Young Women with Endometrial Cancer According to the results of a study published in the Journal of Clinical Oncology, removal of the ovaries may not be necessary in young women treated with hysterectomy for... Continue Reading
More Stages I-III Uterine CancerStages I-IIIA Lung Cancer - Non-Small Cell
Standard Dose of Radiation Therapy Outperforms Higher Dose for Advanced Non-Small Cell Lung Cancer (June 12, 2013)
In a phase III clinical trial, a standard dose of radiation therapy was more effective than a higher dose for the treatment of stage III non-small cell lung cancer (NSCLC). These results will be presented at the 49th Annual Meeting of the American Society... Continue Reading
Stereotactic Body Radiation Improves Lung Cancer Survival (November 9, 2012)Stereotactic body radiation for early-stage, inoperable non-small cell lung cancer yields high overall survival rates and low toxicity compared to conventional radiotherapy, according to the results of a study presented at the annual meeting of the American... Continue Reading
Genetic Study Identifies New Targets for Treating Squamous Cell Lung Cancer (September 19, 2012)Researchers have identified a large variety of genetic alterations that appear to be responsible for the development and growth of squamous cell lung cancer, according to the results of a study published in Nature. The discovery could lead to new targeted... Continue Reading
Higher Radiation Dose Does Not Benefit Lung Cancer Patients (October 13, 2011)Among patients with Stage III non-small cell lung cancer, treatment with a higher dose of radiation therapy does not result in better overall survival than a standard dose of radiation therapy. These results were presented at the 53rd Annual Meeting of... Continue Reading
Elderly, Minorities and Women Under-represented in Lung Cancer Clinical Trials (August 25, 2011)Compared with the demographics of lung cancer in the United States, the elderly, minorities, and women remain vastly under-represented in lung cancer clinical trials. These results were presented at the 14th World Conference on Lung Cancer. Clinical trials... Continue Reading
More Stages I-IIIA Lung Cancer - Non-Small CellStages II-III Bladder Cancer
Robotic Bladder Cancer Surgery Safe and Effective (January 24, 2013)
Robotic-assisted surgery for invasive bladder cancer is effective and results in less bleeding and shorter hospital stays when compared to the traditional open procedure, according to the results of a study published in the Journal of Urology. The bladder... Continue Reading
Adding Chemotherapy to Radiation Reduces Bladder Cancer Recurrence (April 30, 2012)Chemotherapy plus radiation reduces the risk of recurrence in muscle-invasive bladder cancer patients by nearly 50% compared to radiation alone, according to the results of a study published in the New England Journal of Medicine.[1] Bladder cancer is... Continue Reading
Study Explores New Approach to Boosting the Immune System after Cancer Treatment (August 24, 2011)Researchers are seeking participants for a Phase II clinical trial that will explore whether an investigational treatment can help the immune system recover after cancer treatment. Cancer treatments such as chemotherapy and radiation therapy often deplete... Continue Reading
Liposomal Cisplatin Safe for Patients with Renal Insufficiency (June 14, 2011)Liposomal cisplatin (Nanoplatin®), a chemotherapy drug still in clinical trials, does not cause damage to the kidneys and appears to provide at least equal anti-cancer effects as cisplatin (Platinol®) among cancer patients with renal insufficiency.... Continue Reading
New Bladder-preserving Therapy Promising in Bladder Cancer (November 9, 2010)A new bladder-preserving approach to treatment of locally invasive bladder cancer appears promising, both for patients for whom radical cystectomy is indicated and for those previously ineligible for curative treatment. These findings were recently published... Continue Reading
More Stages II-III Bladder CancerStages II-III Breast Cancer
SERMs Reduce Risk of Breast Cancer (June 12, 2013)
Women who take selective estrogen receptor modulators (SERMs) have a 38 percent reduced risk of breast cancer for up to 10 years after diagnosis and treatment, according to the results of a meta-analysis published in The Lancet. A majority of breast cancers... Continue Reading
Breast-Conserving Therapy Comparable to Mastectomy for Women with Early-Stage Triple-Negative Breast Cancer (May 23, 2013)In a study of more than 600 women with early-stage triple-negative breast cancer treated at a single institution, treatment with breast-conserving therapy was as effective as total mastectomy. These results were published in Annals of Surgery Oncology. Breast-conserving... Continue Reading
Lymphoseek Approved for Detecting Lymph Nodes in Breast Cancer and Melanoma (April 10, 2013)The U.S. Food and Drug Administration (FDA) has approved Lymphoseek® (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing... Continue Reading
Oncotype DX Recurrence Score Can Predict Loco-Regional Recurrence in Node-positive, ER-Positive Breast Cancer (April 9, 2013)The Oncotype DX® Recurrence Score® result is a robust predictor of loco-regional recurrence in node-positive, estrogen receptor (ER)-positive patients treated with adjuvant hormonal therapy and chemotherapy, according to the results of a study presented... Continue Reading
Radiation for Breast Cancer Increases Risk of Heart Disease and Heart Attack (March 27, 2013)Exposure to ionizing radiation during radiation therapy for breast cancer may increase the risk of heart attack or heart disease later in life, according to the results of a study published in the New England Journal of Medicine. Many women with breast... Continue Reading
More Stages II-III Breast CancerStages II-III Multiple Myeloma
Zevalin Effective in Relapsed/Refractory Follicular Lymphoma (January 11, 2013)
Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
Pomalidomide Improves Survival in Refractory Multiple Myeloma (January 8, 2013)Pomalidomide plus low-dose dexamethasone (LoDEX) significantly increased progression-free survival and overall survival compared with high-dose dexamethasone (HiDEX) in patients with refractory multiple myeloma, according to the results of a phase III... Continue Reading
MLN9708 “Oral Velcade” Shows Promise in Multiple Myeloma (January 3, 2013)The investigational, oral proteasome inhibitor MLN9708, which is a new version of Velcade® (bortezomib)—may be more effective and better tolerated than the Velcade injections, according to data from a mid-stage study presented at the 54th Annual Meeting... Continue Reading
Velcade Effective for Induction and Maintenance Treatment of Multiple Myeloma (September 7, 2012)Velcade® (bortezomib) during induction and maintenance treatment improves survival in newly diagnosed stage II or III multiple myeloma, according to the results of a study published in the Journal of Clinical Oncology. Multiple myeloma is a cancer of... Continue Reading
Three Studies Show Revlimid Provides Benefits—and Risks—in Multiple Myeloma (May 18, 2012)Maintenance therapy with Revlimid® (lenalidomide) has been shown to significantly improve progression-free survival and time to progression in multiple myeloma, according to the results of three studies published in the New England Journal of Medicine. Multiple... Continue Reading
More Stages II-III Multiple MyelomaStages II-IVA Cervical Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Gemzar® Added to Chemoradiation Improves Survival in Locally Advanced Cervical Cancer (June 8, 2009)Gemzar® Added to Chemoradiation Improves Survival in Locally Advanced Cervical Cancer The combination of Gemzar® (gemcitabine), Platinol® (cisplatin), and concurrent radiation significantly improves survival over single-agent Platinol and radiation... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer (March 8, 2009)Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer Robotically-assisted hysterectomy (RAH) in patients with early-stage cervical cancer is at least as effective as traditional open radical hysterectomy (ORH) and produces fewer complications,... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison... Continue Reading
More Stages II-IVA Cervical CancerStages III-IV Gastric Cancer
Second-Line Docetaxel Improves Survival in Esophageal and Gastric Cancer (April 3, 2013)
Second-line treatment with docetaxel improves overall survival of patients with advanced esophageal and gastric cancer, according to the results of a study presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco. The esophagus is a muscular... Continue Reading
Adjuvant Radiochemotherapy Demonstrates Benefit in Gastric Cancer (September 25, 2012)Adjuvant radiochemotherapy provides strong and persistent benefit in patients who have undergone curative gastric resection, according to the long-term results of a study published in the Journal of Clinical Oncology.[1] Gastric cancer refers to cancer... Continue Reading
XELOX May Improve Survival in Gastric Cancer (June 24, 2011)The chemotherapy regimen referred to as XELOX may improve overall survival compared with observation alone in stages II and III gastric (stomach) cancer; however, data are still immature and longer follow-up is necessary. These results were presented... Continue Reading
Study Evaluates Whole-brain Radiation Following Surgery or Radiosurgery in Cancer Spread to the Brain (November 16, 2010)Results from a randomized Phase III study indicate that whole-brain radiation therapy (WBRT) following removal of one to three brain metastases with surgery or radiosurgery does not improve overall survival or duration of functional independence but does... Continue Reading
Herceptin® Approved for HER2-positive Metastatic Stomach Cancer (November 2, 2010)The U.S. Food and Drug Administration (FDA) has expanded the approval of Herceptin® (trastuzumab) to include the initial treatment of HER2-positive metastatic cancer of the stomach or gastroesophageal junction in combination with chemotherapy.[1] Herceptin... Continue Reading
More Stages III-IV Gastric CancerStages IIIB-IV Lung Cancer - Non-Small Cell
Standard Dose of Radiation Therapy Outperforms Higher Dose for Advanced Non-Small Cell Lung Cancer (June 12, 2013)
In a phase III clinical trial, a standard dose of radiation therapy was more effective than a higher dose for the treatment of stage III non-small cell lung cancer (NSCLC). These results will be presented at the 49th Annual Meeting of the American Society... Continue Reading
Ganetespib Promising for Advanced Lung Cancer (June 6, 2013)In a Phase II clinical trial, second-line treatment with a combination of chemotherapy and the investigational drug ganetespib improved overall survival among patients with advanced lung adenocarcinoma. These results were presented at the 2013 Annual... Continue Reading
Xgeva Improves Survival Over Zometa in Advanced Lung Cancer (November 28, 2012)Patients with advanced lung cancer experienced modest improvement in survival when they received bone-targeted therapy with Xgeva® (denosumab) instead of Zometa® (zoledronic acid), according to the results of a study published in the Journal of Thoracic... Continue Reading
Xalkori Superior to Standard Chemotherapy in ALK-Positive Lung Cancer (October 4, 2012)The targeted therapy Xalkori® (crizotinib) is superior to standard chemotherapy for the treatment of patients with advanced, ALK-positive non-small cell lung cancer, according to the results of a phase III trial presented at the ESMO 2012 Congress of... Continue Reading
Genetic Study Identifies New Targets for Treating Squamous Cell Lung Cancer (September 19, 2012)Researchers have identified a large variety of genetic alterations that appear to be responsible for the development and growth of squamous cell lung cancer, according to the results of a study published in Nature. The discovery could lead to new targeted... Continue Reading
More Stages IIIB-IV Lung Cancer - Non-Small CellStem Cell Transplant
Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma (March 22, 2013)
Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of... Continue Reading
Antiretroviral Drug May Prevent Graft-Versus-Host Disease (August 6, 2012)The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according to the results of a study published in the New... Continue Reading
Mini-Transplants Continue to Show Promise for Older Patients with AML (November 10, 2011)Less toxic cancer treatment followed by an allogeneic stem cell transplant is showing promise for older patients with advanced blood and bone marrow cancers such as acute myeloid leukemia (AML). These results were published in the Journal of the American... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
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Antidepressant Cymbalta May Reduce Pain from Chemotherapy-Induced Peripheral Neuropathy (May 24, 2013)
The antidepressant Cymbalta® (duloxetine) appears to reduce the numbness and tingling associated with taxane or platinum-based chemotherapy, according to the results of a study published in the Journal of the American Medical Association. Peripheral... Continue Reading
Neulasta Significantly Reduces Febrile Neutropenia Among Colorectal Cancer Patients Receiving Chemotherapy Plus Avasatin (February 25, 2013)Neulasta® (pegfilgrastim) significantly reduced the incidence of grade 3/4 febrile neutropenia among patients with locally advanced or metastatic colorectal cancer who received chemotherapy with FOLFOX or FOLFIRI followed by Avastin® (bevacizumab),... Continue Reading
Exercise Reduces Cancer-Related Fatigue (November 30, 2012)Aerobic exercise can relieve the fatigue associated with cancer and its treatment, according to an updated systematic review published in The Cochrane Library. Fatigue is one of the most common side effects of cancer and its treatment. There are many... Continue Reading
Naproxen May Relieve Bone Pain Associated with Neulasta (August 2, 2012)Twice-daily naproxen is effective in reducing the incidence and severity of bone pain associated with the use of Neulasta® (pegfilgrastim), according to the results of a study published in the Journal of Clinical Oncology. Neulasta is a blood cell growth... Continue Reading
Arrhythmia Risk Leads to Label Change for Zofran (July 9, 2012)Interim data from a recent clinical trial has indicated that a 32 mg single dose of Zofran® (ondansetron) may affect the electrical activity of the heart and could predispose patients to develop an abnormal heart rhythm. The U.S. Food and Drug Administration... Continue Reading
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Increase in Number of Women Undergoing Reconstruction Immediately after Mastectomy (January 22, 2013)
There has been a dramatic increase in the number of women undergoing immediate breast reconstruction after mastectomy—and this increase correlates with an increase in the use of implants, according to the results of a study published in Plastic and... Continue Reading
Some Evidence of Mild “Chemo Brain” in Breast Cancer Survivors (September 14, 2012)Breast cancer patients treated with chemotherapy are at risk for mild cognitive deficits (sometimes referred to as chemo brain) after treatment, according to the results of a study published early online in the Journal of Clinical Oncology. A large portion... Continue Reading
Flaxseed Not Effective Against Hot Flashes (June 7, 2011)Flaxseed does not reduce hot flashes among postmenopausal women. These results were presented at the 2011 annual meeting of the American Society of Clinical Oncology. Menopause—when menstrual cycles end and ovarian hormone production drops dramatically—produces... Continue Reading
Predicting Nerve Damage from Paclitaxel (June 6, 2011)The chemotherapy drug paclitaxel can cause nerve damage in some patients. According to a study that will be presented at the 2011 annual meeting of the American Society of Clinical Oncology, specific genetic markers may eventually allow doctors to know... Continue Reading
Weight Lifting May Not Increase Lymphedema Risk Among Breast Cancer Survivors (January 10, 2011)It may be safe for breast cancer survivors to lift weights, including upper-body exercises, without increasing risk for lymphedema. These results were reported in the Journal of the American Medical Association. Lymphedema refers to swelling of the arm... Continue Reading
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Targeted Agent Xalkori May Benefit Children with Anaplastic Lymphoma (May 23, 2012)
The targeted agent Xalkori® (crizotinib) appears to drastically reduce the size of tumors in children with refractory anaplastic large cell lymphoma, according to the results of a phase I study that will be presented at the annual meeting of the American... Continue Reading
Lymphoma During Pregnancy Can Have Good Outcomes (March 14, 2012)Among women who are diagnosed with lymphoma during pregnancy, the outcomes for both mother and baby are often good. This was true for women who began lymphoma treatment during the second or third trimester of pregnancy, as well as women who deferred treatment... Continue Reading
Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist... Continue Reading
Folotyn Benefits Patients with Relapsed or Refractory Peripheral T-Cell Lymphoma (February 3, 2011)In the Phase II PROPEL study, 29% of patients with relapsed or refractory peripheral T-cell lymphoma (a type of non-Hodgkin’s lymphoma) experienced a complete or partial disappearance of detectable cancer following treatment with Folotyn® (pralatrexate).... Continue Reading
Istodax Active against Refractory Cutaneous T-cell Lymphoma (August 31, 2010)Final results from a Phase II clinical trial provide additional evidence that Istodax® (romidepsin) is active against refractory cutaneous T-cell lymphoma. These results were published in the Journal of Clinical Oncology. Cutaneous T-cell lymphoma (CTCL)... Continue Reading
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Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Marijuana May Increase Risk of Testicular Cancer (September 21, 2012)Recreational marijuana use may increase the risk of developing subtypes of testicular cancer that have a worse prognosis, according to the results of a study published early online in the journal Cancer. Testicular cancer is the most common cancer diagnosed... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
More Testicular CancerThroat Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
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BRAF V600E mutation Increases Death Risk in Papillary Thyroid Cancer (June 5, 2013)
The presence of the BRAF V600E mutation is significantly associated with increased cancer-related death among patients with papillary thyroid cancer, according to the results of a study published in the Journal of the American Medical Association. The... Continue Reading
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Selumetinib May Reverse Radioiodine Resistance in Advance Thyroid Cancer (March 28, 2013)The experimental drug selumetinib (AZD6244) may help some patients with advanced thyroid cancer overcome resistance to radioiodine, which is the most effective treatment for the disease, according to the results of a study published in the New England... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Targeted Drug Caprelsa Slows Thyroid Cancer (August 30, 2012)The targeted drug Caprelsa® (vandetanib) delays progression in advanced differentiated thyroid cancer, according to the results of a study published in The Lancet Oncology. The thyroid is a gland in the throat that produces hormones mostly related to... Continue Reading
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Number of Cancer Survivors Expected to Reach 18 Million by 2022 (May 1, 2013)
As of January 2012, there were approximately 13.7 million cancer survivors in the United States and that number is expected to rise by 31 percent to 18 million by 2022, according to the second Annual Report on Cancer Survivorship in the United States published... Continue Reading
Heart Healthy Lifestyle Can Reduce Cancer Risk (April 19, 2013)Following a heart-healthy lifestyle to reduce the risk for heart disease can also help prevent cancer, according to the results of a study published in Circulation. The American Heart Association designed their educational program My Life Check® in order... Continue Reading
Exercise Reduces Cancer-Related Fatigue (November 30, 2012)Aerobic exercise can relieve the fatigue associated with cancer and its treatment, according to an updated systematic review published in The Cochrane Library. Fatigue is one of the most common side effects of cancer and its treatment. There are many... Continue Reading
Statins Linked to Lower Cancer Mortality (November 19, 2012)Cancer patients who used statins (cholesterol-lowering drugs) prior to their cancer diagnosis have a 15 percent lower risk of dying from cancer, according to the results of a study published in then New England Journal of Medicine.[1] Statins are cholesterol-lowering... Continue Reading
Multivitamins May Cut Cancer Risk (October 25, 2012)Daily supplementation with multivitamins modestly but significantly reduced the risk of cancer in healthy male doctors who took them for more than 10 years, according to the results of a study published in the Journal of the American Medical Association. The... Continue Reading
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Mediterranean Diet May Lower Breast Cancer Risk (August 16, 2010)
Postmenopausal women who consume a traditional Mediterranean diet may have a lower risk for breast cancer, according to a study published in the American Journal of Clinical Nutrition. A traditional Mediterranean diet—one that is rich in fish, olive... Continue Reading
More UncategorizedUterine Cancer
Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Number of Cancer Survivors Will Grow to 18 Million by 2022 (June 25, 2012)There will be nearly 18 million cancer survivors in the United States by 2022, according to a report by the American Cancer Society and the National Cancer Institute: Cancer Treatment & Survivorship Facts & Figures[1] and an accompanying journal... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
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Following Lifestyle Recommendations Reduces Risk of Cancer Death (May 15, 2013)
People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent... Continue Reading
Cancer Deaths on the Decline (February 11, 2013)Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence... Continue Reading
Approximately 16% of Worldwide Cancers Caused By Preventable Infections (May 17, 2012)Two million cancer cases each year—or roughly 16 percent of cancers worldwide—are the result of preventable and treatable infections such as human papillomavirus (HPV) and Hepatitis C (HCV), according to the results of a study published in The Lancet... Continue Reading
Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing body of evidence suggests that aspirin may reduce... Continue Reading
Do Complementary Therapies Work? – Ask the expert about herbs, acupuncture, and other complementary therapies (November 4, 2011)Live Web Chat with Barrie R. Cassileth, PhD, Chief, Integrative Medicine Service; Laurance S. Rockefeller Chair Integrative Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), click here for Dr. Cassileth’s bio Dr. Cassileth is a world-renowned... Continue Reading
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